子痫前期的预测进展  

Progresses in prediction of preeclampsia

作　　者：于慧 李格格 付红伟 刘欣颖 冯雪芹 张凡勇[2] YU Hui;LI Gege;FU Hongwei;LIU Xinying;FENG Xueqin;ZHANG Fanyong(Clinical Medical College,Jining Medical University,Jining 272067;Obstetrics Department,Affiliated Hospital of Jining Medical University,Jining 272000,China)

机构地区：[1]济宁医学院临床医学院,山东济宁272067 [2]济宁医学院附属医院产科,山东济宁272000

出　　处：《临床医学研究与实践》2023年第5期191-194,共4页Clinical Research and Practice

基　　金：济宁市重点研发计划项目(No.2019SMNS015)。

摘　　要：子痫前期(PE)是妊娠期特有的严重并发症,发病率高,病情凶险,尤其是早发型子痫前期(EOPE),因此对于PE患者早诊断、早治疗尤为重要。多项研究表明,目前没有理想的单一指标用于预测PE,现有的研究大多是联合多项生化及物理指标进行筛查。本文将对PE的发病机制以及妊娠中期唐氏筛查血清学指标和血糖指标的变化对PE的预测价值做进一步阐述,以便为PE患者早期干预提供一定的理论基础。Preeclampsia(PE)is a serious complication unique to pregnancy,with high incidence and dangerous condition,especially early onset preeclampsia(EOPE).Therefore,early diagnosis and early treatment are particularly important for PE patients.A number of studies have shown that there is no ideal single indicator for predicting PE,and most of the existing studies are combined with multiple biochemical and physical indicators for screening.This article will further elaborate the pathogenesis of PE and the predictive value of the changes of serological indexes and blood glucose indexes of Down's screening in the second trimester of pregnancy for PE,so as to provide a theoretical basis for early intervention of PE patients.

关 键 词：子痫前期 唐氏综合征 胎盘 母体 胰岛素抵抗 

分 类 号：R714[医药卫生—妇产科学]