肥厚型脉络膜疾病谱的研究进展  

Research progress of pachychoroid disease spectrum

作　　者：李璐希 张鹏[1] Li Luxi;Zhang Peng(Department of Ophthalmology,Affiliated Hospital of Northwest University,Xi′an No.3 Hospital,Xi′an 710018,China)

机构地区：[1]西北大学附属医院,西安市第三医院眼科,西安710018

出　　处：《中华眼科杂志》2023年第1期68-72,共5页Chinese Journal of Ophthalmology

摘　　要：肥厚型脉络膜疾病包括中心性浆液性脉络膜视网膜病变、息肉样脉络膜血管病变、肥厚型色素上皮病变、肥厚型脉络膜新生血管病变、局灶性脉络膜凹陷、视盘旁肥厚型脉络膜综合征及周边部渗出性出血性脉络膜视网膜病变等。这类疾病的共同特征是脉络膜血管扩张、通透性增强伴脉络膜厚度增加及视网膜色素上皮异常, 但不同肥厚型脉络膜疾病的临床表现及预后各不相同。随着多模式影像技术的发展及应用, 对于肥厚型脉络膜疾病的认识仍将不断深入。本文对目前已知的肥厚型脉络膜疾病就病理生理学特点、多模式影像特征及其可能的发病机制等进行综述。Pachychoroid disease spectrum encompasses central serous chorioretinopathy,polypoidal choroidal vasculopathy,pachychoroid pigment epitheliopathy,pachychoroid neovasculopathy,focal choroidal excavation,peripapillary pachychoroid syndrome and peripheral exudative hemorrhagic chorioretinopathy,etc.The typical choroidal changes of the spectrum are abnormally dilated pachyvessels,choroidal thickening with overlying retinal pigmentary epithelium changes.However,the clinical manifestations and prognosis of entities described within pachychoroid spectrum are different.Significant advances in multimodal imaging have enabled a deeper understanding of the pachychoroid disease spectrum.This paper reviews the pathophysiological alterations,multimodal imaging features and possible pathogenesis of pachychoroid disease spectrum.

关 键 词：中心性浆液性脉络膜视网膜病变 脉络膜疾病 脉络膜新生血管化 息肉 视网膜疾病 视网膜色素上皮 体层摄影术 光学相干 荧光素血管造影术 

分 类 号：R773.4[医药卫生—眼科]