腹腔镜下保留自主神经的广泛子宫切除术治疗宫颈癌的疗效及对尿动力学参数的影响  

Effect of laparoscopic nerve sparing radical hysterectomy in the treatment of cervical cancer and its impact on urodynamic parameter

作　　者：郑春兰[1] 崔淑萍 张婵丽 ZHENG Chunlan;CUI Shuping;ZHANG Chanli(Department of Obstetrics and Gynecology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,He’nan,China)

机构地区：[1]郑州大学第一附属医院妇产科,郑州450000

出　　处：《癌症进展》2023年第1期62-65,共4页Oncology Progress

摘　　要：目的探讨腹腔镜下保留自主神经的广泛子宫切除术(LNSRH)治疗宫颈癌的疗效及对尿动力学参数的影响。方法将120例宫颈癌患者按照手术方案的不同分为对照组64例和观察组56例,对照组患者采用腹腔镜下广泛性全子宫切除术(LRH),观察组患者采用LNSRH,比较两组患者手术相关指标、并发症发生率、膀胱功能指标、尿动力学参数及生活质量。结果两组患者手术时间、阴道切除长度、淋巴结清扫数目及术中出血量比较,差异均无统计学意义(P﹥0.05)。观察组患者尿潴留发生率低于对照组,差异有统计学意义(P﹤0.05)。观察组患者尿失禁及膀胱功能障碍发生率均低于对照组,术后拔除导尿管时间短于对照组,差异均有统计学意义(P﹤0.05)。手术后,两组患者残余尿量(RUV)均降低,最大尿道压(MUP)、膀胱容量均升高,且观察组患者RUV低于对照组,MUP、膀胱容量均高于对照组,差异均有统计学意义(P﹤0.05)。手术后6个月,两组患者社会/家庭状况、情感状况、生理状况和功能状况评分均升高,且观察组患者社会/家庭状况、情感状况、生理状况和功能状况评分均高于对照组,差异均有统计学意义(P﹤0.05)。结论LNSRH能有效改善宫颈癌患者的膀胱功能,提高患者的生活质量。Objective To investigate the effect of laparoscopic nerve sparing radical hysterectomy(LNSRH)in the treatment of cervical cancer and its impact on urodynamic parameters.Method A total of 120 patients with cervical cancer were divided into control group of 64 cases and observation group of 56 cases according to different surgical regimens.The patients in the control group received laparoscopic radical hysterectomy(LRH),and the patients in the observation group received LNSRH.The surgery-related indicators,the incidence of complications,bladder function indicators,urodynamic parameters,and quality of life were compared between the two groups.Result There were no significant differences in operation time,length of vaginal resection,the number of lymph nodes dissected,and intraoperative blood loss volume between the two groups(P>0.05).The incidence of urinary retention in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).The incidences of urinary incontinence and bladder dysfunction in the observation group were lower than those in the control group,and the time to remove the urinary catheter after the operation was shorter than that in the control group,and the differences were statistically significant(P<0.05).After the operation,the residual urine volume(RUV)decreased,the maximal urethral pressure(MUP)and bladder capacity increased in either group,moreover,the RUV of the observation group was lower than that of the control group,and the MUP and bladder capacity were higher than those of the control group,and the differences were statistically significant(P<0.05).Six months after the operation,the scores of social/family state,emotional state,physiological state,and function state in either group increase,moreover,the scores of social/family state,emotional state,physiological state,and function state of the observation group were higher than those of the control group,and the differences were statistically significant(P<0.05).Conclusion LNSRH co

关 键 词：腹腔镜下保留自主神经的广泛子宫切除术 腹腔镜下广泛性全子宫切除术 宫颈癌 疗效 尿动力学参数 

分 类 号：R737.33[医药卫生—肿瘤]