Research progress of TRIMs protein family in tumors  

作　　者：YUANYUAN HUANG HONGMEI WU RUYUAN LIU SONG JIN WEILAI XIANG CHANG YANG LI XU XIAONIAN ZHU 

机构地区：[1]Department of Health Toxicology,School of Public Health,Guilin Medical University,Guilin,541199,China

出　　处：《BIOCELL》2023年第3期445-454,共10页生物细胞（英文）

基　　金：supported by the National Natural Science Foundation of China(82060607,81860586);the Natural Science Foundation of Guangxi Province(2020GXNSFDA297010).

摘　　要：The tripartite motif(TRIMs)protein family has E3 ubiquitin ligase activity among most of its members.They participate in multiple cellular processes and signaling pathways in living organisms,including cell cycle,growth,and metabolism,and mediate chromatin modification,transcriptional regulation,post-translational modification,and cellular autophagy.Previous studies have confirmed that the TRIMs protein family is involved in the development of various cancers and correlated with the prognosis of tumor patients.Here we summarize the biological roles of the TRIMs protein family in cancers.

关 键 词：TRIMs protein family Liver cancer Lung cancer Colorectal cancer Breast cancer Gastric cancer 

分 类 号：R737.9[医药卫生—肿瘤]