牙髓血运重建术对慢性根尖周炎患者牙冠根比与根管壁厚度的影响  

Effect of pulp revascularization on crown root ratio to root canal wall thickness in patients with chronic periapical inflammation

作　　者：张钰凡 Zhang Yufan(The Affiliated Stomatological Hospital of Dalian Medical University,Dalian,Liaoning 116023)

机构地区：[1]大连医科大学口腔医学院附属口腔医院,辽宁大连116023

出　　处：《基层医学论坛》2023年第4期11-14,共4页The Medical Forum

摘　　要：目的 探讨牙髓血运重建术对慢性根尖周炎(CAP)患者牙冠根比与根管壁厚度的影响。方法 按随机数字表法将2019年2月-2021年2月大连医科大学口腔医学院附属口腔医院收治的94例CAP患者分为治疗组(47例)与常规组(47例),治疗组行牙髓血运重建术治疗,常规组行根尖诱导成形术治疗。对比2组治疗效果和牙骨质样组织沉积率、牙冠根比、根管壁厚度、干扰素γ诱导蛋白(IP)-10、趋化因子配体21(CCL21)、相关生长因子水平。结果治疗组治疗总有效率为100.00%,高于常规组的85.11%,差异有统计学意义(P<0.05);治疗组牙骨质样组织沉积率为(68.40±12.29)%,高于对照组的(57.31±16.79)%,差异有统计学意义(P<0.05);术后4周2组根管壁厚度均高于术前,牙冠根比低于术前,且治疗组牙冠根比较常规组低,根管壁厚度较常规组高,差异有统计学意义(P<0.05);术后4周2组IP-10、CCL21水平均高于术前,但治疗组低于常规组,差异有统计学意义(P<0.05);术后4周2组碱性成纤维细胞生长因子(b FGF)、血管内皮生长因子(VEGF)水平均高于术前,但治疗组低于常规组,差异有统计学意义(P<0.05)。结论 牙髓血运重建术能够有效减小CAP患者牙冠根比,提高根管壁厚度,减轻炎症反应,降低牙组织相关生长因子水平,改善患牙病变。Objective To investigate the effect of dental pulp reascularization on the tooth crown root ratio and root canal wall thickness in patients with chronic periapical periodontitis(CAP). Methods According to the method of random number table, 94 patients with CAP admitted to the Affiliated Stomatological Hospital of Dalian Medical University School of Stomatology from February 2019 to February 2021 were divided into the treatment group(47 cases)and the conventional group(47 cases).The treatment group was treated with pulp revascularization, and the conventional group was treated with apical induction plasty.The treatment effects of the two groups and the rate of cementoid tissue deposition,crown-root ratio,root wall thickness,interferon-induced protein(IP)-10,chemokine ligand 21(CCL21),and related growth factors were compared. Results The total treatment efficiency of the treatment group was 100.00%,higher than 85.11% of the conventional group,the difference was statistical significant(P<0.05);The rate of cemented bone-like tissue deposition in the treatment group(68.40±12.29)%,higher than that in the control group(57.31 ±16.79)%,the difference was statistical significant(P<0.05);Higher root canal wall thickness in both groups at 4 weeks than before surgery,the root crown ratio was lower than before surgery,the treatment group was lower than the conventional group,root pipe wall thickness is higher than that in the conventional group,the difference was statistical significant(P<0.05);The levels of IP-10 and CCL21 were higher in both groups at 4 weeks than before surgery,however,the IP-10 and CCL21 levels were lower at 4 weeks after the treatment group than in the conventional group,the difference was statistical significant(P<0.05);The levels of alkaline fibroblast growth factor(bFGF)and vascular endothelial growth factor(VEGF)at 4 weeks after the surgery were higher than before the surgery,however,the bFGF and VEGF levels at 4weeks in the treatment group were lower than those in the conventional group,the differe

关 键 词：慢性根尖周炎 牙髓血运重建术 根尖诱导成形术 牙冠根比 根管壁厚度 

分 类 号：R781.34[医药卫生—口腔医学]