3D打印激光工作鞘连接膀胱镜联合钬激光整块切除非肌层浸润性膀胱肿瘤的安全性及有效性  

Safety and efficacy of 3D-printed laser working sheath combined with cystoscope and holmium laser in total resection of non-muscular invasive bladder tumors

作　　者：李强 李伟[1] 曹贵华 刘亮程 杜建平[1] 黄贵闽[1] LI Qiang;LI Wei;CAO Guihua;LIU Liangcheng;DU Jianping;HUANG Guimin(Department of Urology,People's Hospital of Leshan,Sichuan Leshan 614000,China.)

机构地区：[1]乐山市人民医院泌尿外科,四川乐山614000

出　　处：《现代肿瘤医学》2023年第5期894-898,共5页Journal of Modern Oncology

基　　金：四川省医学科研课题计划(编号:S20053)。

摘　　要：目的:探讨经尿道膀胱肿瘤整块切除术中应用3D打印激光工作鞘连接膀胱镜联合钬激光的安全性及有效性。方法:回顾性分析92例非肌层浸润性膀胱肿瘤的临床资料,其中采用3D打印制作的激光工作鞘匹配F21膀胱镜联合钬激光整块切除手术组(激光工作鞘组)52例,经尿道电切手术组(电切镜组)40例。对比两组患者手术时间、膀胱冲洗时间、病检合格率、并发症发生率及术后随访复发率,所得数据进行统计学分析。结果:92例患者均完成手术,其中电切镜组4例患者因生理性尿道狭小,电切镜无法置入改行开放膀胱部分切除术。两组患者手术时间差异无统计学意义(P>0.05);激光工作鞘组的病检合格率高于电切镜组,并发症发生率、术后复发率低于电切镜组。结论:3D打印激光工作鞘连接F21膀胱镜联合钬激光行膀胱肿瘤整块切除术是安全、有效的。Objective:To investigate the safety and efficacy of 3D-printed laser working sheath connecting with cystoscope with holmium laser for en bolc transurethral resection of bladder tumor.Methods:The clinical data of 92 cases of non-muscular invasive bladder tumor were analyzed retrospectively, including laser working sheath matching F21 cystoscope combined with holmium laser block resection group(laser working sheath group, n=52) and transurethral resection group(electroresection group, n=40).The operation time, bladder irrigation time, qualified rate of pathological examination, complication rate and postoperative follow-up recurrence rate were compared between the two groups, and the data were statistically analyzed.Results:All the 92 patients completed the operation, of which 4 patients in the electroresection group underwent open partial cystectomy because of physiological urethral stricture.There was no significant difference in operation time between the two groups(P>0.05),but the qualified rate of pathological examination in the laser working sheath group was higher than that in the electroresection group, and the complication rate and postoperative recurrence rate in the laser working sheath group were lower than those in the electroresection group.Conclusion:3D-printed laser working sheath connecting with F21 cystoscope with holmium laser for en bloc transurethral resection is safe, effective and novel treatment of bladder cancer patients.

关 键 词：3D打印 钬激光 膀胱肿瘤 整块切除 

分 类 号：R737.14[医药卫生—肿瘤]