Carbon-coated magnetic particles increase tissue temperatures after laser irradiation  

作　　者：Shupeng Liu Na Chen Fufei Pang Zhengyi Chen Tingyun Wang 

机构地区：[1]Key Laboratory of Specialty Fiber Optics and Optical Access Networks Shanghai University,149 Yanchang Road Shanghai 200072,P.R.China [2]Institute of Biomedical Engineering,Shanghai University 149 Yanchang Road,Shanghai 200072,P.R.China

出　　处：《Journal of Innovative Optical Health Sciences》2015年第5期50-55,共6页创新光学健康科学杂志（英文）

基　　金：This work is supported by the Natural Science Foundation of China(NSFC) (61027015,61177088,61107076);the National Program on Key Basic Research Project (973 Program,2012CB723405).

摘　　要：Purpose:This work focused on the investigation the hyperthermia performance of the carboncoated magnetic particles(CCMPs)in laser-induced hyperthermia.Materials and methods:We prepared CCMPs using the organic carbonization method,and then characterized them with transmission electron microscopy(TEM),ultraviolet-visible(UV-Vis)spectrophotometry,vibrating sample magnetometer(VSM)and X-ray di®raction(XRD).In order to evaluate their performance in hyperthermia,the CCMPs were tested in laser-induced thermal therapy(LITT)experiments,in which we employed a fully distributedfiber Bragg grating(FBG)sensor to profile the tissue's dynamic temperature change under laser irradiation in real time.Results:The sizes of prepared CCMPs were about several micrometers,and the LITT results show that the tissue injected with the CCMPs absorbed more laser energy,and its temperature increased faster than the contrast tissue without CCMPs.Conclusions:The CCMPs may be of great help in hyperthermia applications.

关 键 词：Carbon-coated magnetic particles HYPERTHERMIA laser 

分 类 号：R73[医药卫生—肿瘤]