Characterizing UVB-induced skin tumor process using optical coherence tomography  

作　　者：Shulian Wu Zheng Huang Yunxia Wang Hui Li 

机构地区：[1]Key Lab of OptoElectronic Science and Technology for Medicine Fujian Provincial Key Lab of Photonic Technology College of Photonic and Electronic Engineering Fujian Normal University Fuzhou 350007,Fujian,P.R.China

出　　处：《Journal of Innovative Optical Health Sciences》2016年第5期30-37,共8页创新光学健康科学杂志（英文）

基　　金：supported by the National Natural Science Foundation of China(61178089);the Natural Science Foundation of Fujian Province(2014J01226);Foundation of Fujian Educational Committee(JA14093).

摘　　要：The incidence of nonmelanoma skin cancer is rising worldwide.The major cardinogenic factor for most skin cancers is solar ultraviolet light,in particular,the chronic exposure to UVB(280-320nm).In this study,the optical characteristics of skin canceration process induced by UVB were analyzed.Optical coherence tomography(OCT)was used for monitoring the morphologic changes and compared with histological analysis.Meanwhile,the optical property,such as the attenuation cofficient(A4)was systematically extracted and analyzed.In addition,characteristic text ures,including energy,entropy and correlation were revealed from OCT images.Results suggest that OCT is a useful tool for monitoring the process of UVB-induced skin cancer and changes of optical property during this process.

关 键 词：Skin cancer UVB morphologic change attenuation coefficient TEXTURE 

分 类 号：R73[医药卫生—肿瘤]