良性阵发性位置性眩晕患者椎—基底动脉系统血流动力学参数与平衡功能的相关性及评估病情程度价值  

The correlation between the hemodynamic parameters of the vertebra-basal artery system and the balance function in patients with benign paroxysmal positional vertigo and the value of evaluating the severity of the disease

作　　者：张敬[1] 李锦[1] 王佳[1] 纪叶[1] 韩敬哲[2] Zhang Jing;Li Jin;Wang Jia;Ji Ye;Han Jingzhe(Department of Neurological Function Inspection,Hengshui People's Hospital,Hengshui 053000,China;The First Department of Neurology,Hengshui People's Hospital,Hengshui 053000,China)

机构地区：[1]哈励逊国际和平医院神经功能检查科,衡水053000 [2]哈励逊国际和平医院神经内一科,衡水053000

出　　处：《广西医科大学学报》2023年第1期140-146,共7页Journal of Guangxi Medical University

基　　金：2019年河北省医学科学研究课题(No.20191782)。

摘　　要：目的:探讨良性阵发性位置性眩晕(BPPV)患者椎—基底动脉系统血流动力学参数与平衡功能的相关性及对病情程度的评估价值。方法:选取2018年6月至2020年9月我院收治的117例BPPV患者作为研究对象,比较不同眩晕分级患者临床资料、椎—基底动脉系统血流动力学参数[收缩期峰值流速(PSV)、舒张末期血流速度(EDV)、平均血流速度(MFV)、阻力指数(RI)、搏动指数(PI)]、平衡功能[前庭症状指数(VSI)、Berg平衡量表(BBS)、计时平衡时间],分析椎—基底动脉系统血流动力学参数与平衡功能的相关性及其对BPPV患者病情程度的评估价值。结果:随着BPPV患者眩晕分级加重,椎—基底动脉系统PSV、EDV、MFV、BBS评分、计时平衡时间下降,RI、PI及VSI指数升高(P<0.05)。BPPV患者椎—基底动脉系统PSV、EDV、MFV与VSI评分呈负相关关系,与BBS评分、计时平衡时间呈正相关关系,RI、PI与VSI评分呈正相关关系,与BBS评分、计时平衡时间呈负相关关系(P<0.05)。椎—基底动脉系统血流动力学参数评估BPPV患者病情程度AUC均>0.7。结论:椎—基底动脉血流动力学参数与BPPV患者平衡功能密切相关,监测上述参数变化情况可辅助临床判断病情程度,指导个性化治疗方案制定。Objective: To investigate the correlation between the hemodynamic parameters of the vertebral-basal artery system and the balance function of patients with benign paroxysmal positional vertigo(BPPV) and the evaluation value of the severity of the disease. Methods: A total of 117 BPPV patients in our hospital from June 2018to September 2020 were selected as the research objects. The clinical data and hemodynamic parameters of the vertebra-basal artery system [peak systolic velocity(PSV), end of diastolic velocity(EDV), mean flow rate(MFV), resistance index(RI), pulsatility index(PI)], balance function [vestibular symptom index(VSI), Berg balance scale(BBS), balance time of timing] of patients with different vertigo grades were compared. The correlation between the hemodynamic parameters of the vertebral-basal artery system and the balance function and the evaluation value of the disease severity of BPPV patients were analyzed. Results: With the aggravation of vertigo classification in patients with BPPV, the PSV, EDV, MFV, BBS scores of the vertebral-basal artery system, and timing balance time decreased, and the RI, PI and VSI indexes increased(P<0.05). PSV, EDV, and MFV of the vertebral-basal artery system of BPPV patients were negatively correlated with VSI scores, and positively correlated with BBS scores and the balance time of timing. RI and PI were positively correlated with VSI scores,and negatively correlated with BBS scores and balance time of timing(P<0.05). AUC of patients with BPPV evaluated by hemodynamic parameters of vertebral-basal artery system were more than 0.7. Conclusion:The hemodynamic parameters of the vertebral-basilar artery system are closely related to the balance function of patients with BPPV. Monitoring the changes of the above parameters can assist the clinical judgment of the severity of the disease and guide the formulation of personalized treatment plans.

关 键 词：良性阵发性位置性眩晕 椎—基底动脉系统 血流动力学 平衡功能 病情程度 

分 类 号：R741.02[医药卫生—神经病学与精神病学]