Hydrocephalic cerebrospinal fluid flowing rotationally with pulsatile boundaries:A mathematical simulation of the thermodynamical approach  

作　　者：Hemalatha Balasundaram Senthamilselvi Sathyamoorthi Unai Fernandez-Gamiz Samad Noeiaghdam Shyam Sundar Santra 

机构地区：[1]Department of Mathematics,VISTAS,Vels University,Zamin Pallavaram,Chennai,Tamilnadu [2]Nuclear Engineering and Fluid Mechanics Department,University of the Basque Country UPV/EHU,Nieves Cano 12,01006,Vitoria-Gasteiz,Spain [3]Industrial Mathematics Laboratory,Baikal School of BRICS,Irkutsk National Research Technical University,Irkutsk,664074,Russia [4]Department of Applied Mathematics and Programming,South Ural State University,Lenin prospect 76,Chelyabinsk,454080,Russia [5]Department of Mathematics,Applied Science Cluster,University of Petroleum and Energy Studies,Dehradun,Uttarakhand,248007,India [6]Department of Mathematics,JIS College of Engineering,Kalyani,West Bengal 741235,India

出　　处：《Theoretical & Applied Mechanics Letters》2023年第1期79-86,共8页力学快报（英文版）

基　　金：supported by the government of the Basque Country for the ELKARTEK21/10 KK-2021/00014 and ELKARTEK22/85 research programs,respectively。

摘　　要：To study the kinematics of flow rate and ventricular dilatation,an analytical perturbation approach of hydrocephalus has been devised.This research provides a comprehensive investigation of the characteristics of cerebrospinal fluid(CSF)flow and pressure in a hydrocephalic patient.The influence of hydrocephalic CSF,flowing rotationally with realistic dynamical characteristics on pulsatile boundaries of subarachnoid space,was demonstrated using a nonlinear controlling system of CSF.An analytical perturbation method of hydrocephalus has been developed to investigate the biomechanics of fluid flow rate and the ventricular enlargement.In this paper presents a detailed analysis of CSF flow and pressure dynamics in a hydrocephalic patient.It was elaborated with a nonlinear governing model of CSF to show the influence of hydrocephalic CSF,flowing rotationally with realistic dynamical behaviors on pulsatile boundaries of subarachnoid space.In accordance with the suggested model,the elasticity factor changes depending on how much a porous layer,in this case the brain parenchyma,is stretched.It was improved to include the relaxation of internal mechanical stresses for various perturbation orders,modelling the potential plasticity of brain tissue.The initial geometry that was utilised to create the framework of CSF with pathological disease hydrocephalus and indeed the output of simulations using this model were compared to the actual progression of ventricular dimensions and shapes in patients.According to this observation,the non-linear and elastic mechanical phenomena incorporated into the current model are probably true.Further modelling of ventricular dilation at a normal pressure may benefit from the existence of a valid model whose parameters approximate genuine mechanical characteristics of the cerebral cortex.

关 键 词：Brain parenchyma Cerebrospinal fluid HYDROCEPHALUS Ventricular elasticity Intracranial pressure differences 

分 类 号：O352[理学—流体力学]