重症急性胰腺炎并发胰性脑病的诊疗进展  

Progress in diagnosis and treatment of severe acute pancreatitis complicated with pancreatic encephalopathy

作　　者：吴月 孔婧[1] 刘宇洋 许高凡 王晓 何云云 孟杨杨 江雨洁 周秉舵[1] Wu Yue;Kong Jing;Liu Yu-yang;Xu Gao-fan;Wang Xiao;He Yun-yun;Meng Yang-yang;Jiang Yu-jie;Zhou Bing-duo(Department of Gastroenterology,Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China)

机构地区：[1]上海中医药大学附属岳阳中西医结合医院消化内科,上海200437

出　　处：《中国急救医学》2023年第2期156-160,共5页Chinese Journal of Critical Care Medicine

基　　金：国家自然科学基金(82004264);国家自然科学基金面上项目(81973809);上海市卫健委中医药创新团队科研项目(2022CX002);上海市卫健委名老中医学术经验研究工作室项目(SHGZS-202203);上海市卫健委中医药高层次人才引领计划[ZY(2021-2023)-0403]。

摘　　要：胰性脑病(PE)是重症急性胰腺炎(SAP)罕见的并发症,临床多表现为定向力障碍、意识模糊、妄想或出现幻觉等精神神经症状,并伴有弥漫性脱髓鞘和脑白质改变,其病情凶险,病死率高,临床诊断易延误、混淆。目前关于PE的研究尚少,本文就PE的发病机制、诊断要点、治疗研究进展进行综述,旨在为临床及科研实践提供帮助。Pancreatic encephalopathy(PE)is a rare complication of severe acute pancreatitis(SAP),its clinical manifestations are mental and neurological symptoms such as disorientation,confusion of consciousness,delusion or hallucination,and accompanied by diffuse demyelination and brain white matter changes.Its condition is dangerous and has a high mortality rate,and the clinical diagnosis is easy to be delayed and confused.At present,there are few studies on PE.This article reviews the pathogenesis,diagnosis and treatment of PE in order to provide help for clinical and scientific research practice.

关 键 词：重症急性胰腺炎(SAP) 胰腺脑病(PE) 发病机制 诊断与治疗 

分 类 号：R576[医药卫生—消化系统]