Comprehensive analysis of mRNA poly(A)tails by PAIso-seq2  

作　　者：Yusheng Liu Hu Nie Yiwei Zhang Falong Lu Jiaqiang Wang 

机构地区：[1]College of Life Science,Northeast Forestry University,Harbin 150040,China [2]State Key Laboratory of Molecular Developmental Biology,Institute of Genetics and Developmental Biology,Innovative Academy of Seed Design,Chinese Academy of Sciences,Beijing 100101,China [3]University of Chinese Academy of Sciences,Beijing 100049,China [4]College of Life Science,Northeast Agricultural University,Harbin 150030,China

出　　处：《Science China(Life Sciences)》2023年第1期187-190,共4页中国科学（生命科学英文版）

基　　金：supported by the National Key Research and Development Program of China(2018YFA0107001,2020YFA0804000);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA24020203);the CAS Project for Young Scientists in Basic Research(YSBR-012);the National Natural Science Foundation of China(31970588,32170606);the Natural Science Foundation of Heilongjiang province(YQ2020C003);the China Postdoctoral Science Foundation(2020M670516,2020T130687);the State Key Laboratory of Molecular Developmental Biology。

摘　　要：Dear Editor,Poly(A)tails are added to the 3’-end of most mRNAs(Colgan and Manley,1997;Yu and Kim,2020).The regulatory roles of poly(A)tails have long been underestimated due to technical difficulties in analyzing homopolymers(Chang et al.,2014;Subtelny et al.,2014).Several methods were recently developed to accurately measure their length(Chang et al.,2014;Legnini et al.,2019;Liu et al.,2019;Liu et al.

关 键 词：POLY(A) TAILS ANALYSIS 

分 类 号：Q943.2[生物学—植物学]