女性乳腺癌患者前哨淋巴结转移的危险因素分析  

Risk factors of sentinel lymph node metastasis in female breast cancer patients

作　　者：左永刚 温玉清 田艳艳 夏书官 刘家才 Zuo Yonggang;Wen Yuqing;Tian Yanyan;Xia Shuguan;Liu Jiacai(Department of Breast and Thyroid Surgery,Huaihe Hospital of Henan University,Kaifeng 475000,Chin)

机构地区：[1]河南大学淮河医院乳腺甲状腺外科,开封475000

出　　处：《临床医学》2022年第11期5-8,共4页Clinical Medicine

基　　金：2021年度河南省科技厅课题(202102310102)。

摘　　要：目的 探讨女性乳腺癌患者前哨淋巴结(SLN)转移的危险因素。方法 回顾性分析2019年12月至2021年12月河南大学淮河医院收治的43例SLN转移与47例SLN未转移女性乳腺癌患者的相关资料,采用多元Logistic回归分析患者SLN转移的危险因素。结果 单因素分析显示,SLN转移与未转移患者肿瘤大小、病理分型、组织学分级、脉管是否浸润、人类表皮生长因子受体-2(HER-2)等因素比较,差异有统计学意义(P<0.05);多元Logistic回归分析结果显示,肿瘤大小、组织学分级、脉管是否浸润、HER-2是乳腺癌患者SLN转移的危险因素(P<0.05),病理分型不是乳腺癌患者SLN转移的危险因素(P>0.05)。结论 肿瘤大小、组织学分级、脉管是否浸润、HER-2是乳腺癌患者SLN转移的危险因素。Objective To investigate the risk factors of sentinel lymph node(SLN) metastasis in female breast cancer patients. Methods The relevant data of 43 female breast cancer patients with SLN metastasis and 47 female breast cancer patients without SLN metastasis who were admitted to Huaihe Hospital of Henan University from December 2019 to December 2021 were retrospectively analyzed. Multivariate logistic regression analysis was performed to screen the risk factors of SLN metastasis. Results Univariate analysis showed that tumor size, pathological type, histological grade, vascular invasion, and HER-2 showed significant differences between patients with SLN metastasis and those without metastasis(P<0.05). Multivariate logistic regression analysis showed that tumor size, histological grade, vascular invasion, HER-2 were risk factors for SLN metastasis in breast cancer patients(P<0.05), and pathological classification was not a risk factor for SLN metastasis in patients with breast cancer(P>0.05). Conclusions Tumor size, histological grade, vascular invasion and HER-2 are risk factors for SLN metastasis in breast cancer patients.

关 键 词：女性乳腺癌 前哨淋巴结转移 危险因素 

分 类 号：R737.9[医药卫生—肿瘤]