呋喃酮的结构修饰与生物活性在实验教学研究  

Study on Structural Modification and Biological Activity of Furanone in Experimental Teaching

作　　者：霍景沛[1,2] 陈宝钊 黄泽锋 黄培源 林发开 Huo Jingpei;Chen Baozhao;Huang Zefeng;Huang Peiyuan;Lin Fakai(College of Materials Science and Hydrogen Energy,Foshan University,Foshan 528000;Guangdong Key Laboratory for Hydrogen Energy Technologies,Foshan University,Foshan 528000;Li Changrong Rubber Co.,Ltd.,Huizhou 516082,China)

机构地区：[1]佛山科学技术学院,材料科学与氢能学院,广东佛山528000 [2]佛山科学技术学院,广东省氢能技术重点实验室,广东佛山528000 [3]惠州李长荣橡胶有限公司,广东惠州516082

出　　处：《广东化工》2023年第1期211-212,217,共3页Guangdong Chemical Industry

基　　金：佛山科学技术学院博士启动基金(CGG040947),实验室开放基金,学术基金,大学生创新创业训练计划。

摘　　要：简单介绍了呋喃酮的结构修饰、基团筛选和抗宫颈癌的生物活性。详细探讨了苯并咪唑基团对呋喃酮修饰在生物活性实验教学的影响。其中阐述呋喃酮化合物在抗肿瘤药物领域的应用。最后展望了呋喃酮结构单元的未来药物合成与实验教学发展方向。The structural modification,group screening and biological activity of furanone were briefly introduced.The effect of benzimidazole group on furanone modification in experimental teaching of biological activity was discussed in detail.The application of furanone compounds in the field of antitumor drugs is described.Finally,the future development direction of drug synthesis and experimental teaching of furanone structural unit was prospected.

关 键 词：呋喃酮 苯并咪唑 抗肿瘤药物 实验教学 抗宫颈癌 生物活性 

分 类 号：TQ[化学工程]