Pharmacognostic and phytochemical studies as an invaluable approach for correct identification of medicinal plants:The case of Artemisia vulgaris L.substituted for Artemisia annua L.in Western Uganda  

作　　者：Ivan Kahwa Clement Olusoji Ajayi Reenu Yadav Nagendra Singh Chauhan Kamal Shah Abdelgadir Alamin Abdelgadir Efrata Ashuro Shegena Salome Daniel Timothy Omara John Baptist Asiimwe Hilda Ikiriza Shabnoor Iqbal Casim Umba Tolo Anke Weisheit Patrick Engeu Ogwang 

机构地区：[1]Pharm-BioTechnology and Traditional Medicine Centre,Mbarara University of Science and Technology,P.O.Box 1410,Mbarara,Uganda [2]Department of Pharmacy,Faculty of Medicine,Mbarara University of Science and Technology,P.O.Box 1410,Mbarara,Uganda [3]Department of Pharmacy,IES University,Bhopal-462044,Madhya Pradesh,India [4]Drugs Testing Laboratory Avam Anusandhan Kendra,Raipur(CG)492010,India [5]Institute of Pharmaceutical Research,GLA University,Mathura,Uttar Pradesh 281406,India [6]Department of Pharmacognosy,Faculty of Pharmacy,University of Gezira,P.O Box 20,Wad Madani,Sudan [7]Department of Pharmaceutics and Pharmacy Practice,Kampala International University,P.O.Box 9790,Dares Salaam,Tanzania [8]Institute of Chemistry of Renewable Resources,Department of Chemistry,University of Natural Resources and Life Sciences Vienna(BOKU),Konrad-Lorenz-Straße 24,3430,Tulln an der Donau,Austria [9]Aga Khan University,P.O.Box 8842,Kampala,Uganda [10]Department of Biology,Mbarara University of Science and Technology,P.O.Box 1410,Mbarara,Uganda [11]Department of Zoology,Government College University,Faisalabad,Punjab 38000,Pakistan

出　　处：《TMR Integrative Medicine》2023年第4期1-13,共13页TMR整合医学

基　　金：This study was financially supported by the Pharm-Biotechnology and Traditional Medicine Centre(PHARMBIOTRAC).We would like to thank and acknowledge Pharm-Biotechnology and Traditional Medicine Centre hosted at Mbarara University of Science and Technology for funding the study,Mrs.Venerandah Biryabarema Bushenyi and Africa Volunteer Association-Kamwenge for providing us with the study plants.The authors also thank Mr.Gershom Muganga who was a research assistant during the study.

摘　　要：Background:Different parts of Artemisia vulgaris L.(A.vulgaris)are ethno-medicinally used as an emmenagogue and for the treatment of ailments such as malaria fever,ulcers,and cancer.However,anecdotal evidence shows that the plant is often substituted for Artemisia annua L.(A.annua)by herbalists in Western Uganda due to similarities in their morphology.Misidentification of medicinal plants and mislabelling of herbal products have been incriminated in toxicity and adverse health outcomes in traditional medicine practise.Because safety continues to be a major issue with the use of herbal remedies,it becomes imperative therefore that medicinal plants should be correctly identified.Methods:This study focused on investigating the macroscopic,microscopic,physicochemical characteristics and phytochemical composition of A.vulgaris leaves compared to A.annua to ease its correct identification.Results:The results showed that there are some colour differences between the leaves of the two species,with a close arrangement of microscopic features but different leaf constants.The leaves of the two Artemisia species had similar tastes,but their shapes and colours(greenish-yellow for A.annua and dark green for A.vulgaris)can be used by the local community to distinguish between them.The artemisinin content was higher in A.vulgaris leaves(1.72%)than in A.annua(1.43%),but the reverse was observed for the total flavonoid content.Conclusion:This observation could justify the change in the use of A.vulgaris by the indigenous community in western Uganda.Further studies should consider the pharmacognostic comparison of A.annua with other species in the genus Artemisia and the use of molecular techniques such as DNA barcoding.

关 键 词：ARTEMISININ traditional medicine MISIDENTIFICATION microscopic studies 

分 类 号：R28[医药卫生—中药学]