2型糖尿病女性月经史及生育史与甲状腺癌发病风险的关系  

作　　者：刘颖 苗婷茹 陈婷[1] 姚定国[1] 

机构地区：[1]浙江中医药大学附属第一医院,310006 [2]浙江省人民医院,310014

出　　处：《浙江临床医学》2022年第12期1807-1808,共2页Zhejiang Clinical Medical Journal

摘　　要：目的调查2型糖尿病、女性月经史及生育史与甲状腺癌发病风险的关系,旨在为甲状腺癌的早期预防提供科学依据.方法采用自行设计问卷对2018年至2019年期间经浙江中医药大学附属第一医院确诊的202例杭州地区甲状腺癌患者和按合适方法1:1配对选择的202例甲状腺B超正常者做为对照分别进行问卷调查.结果单因素分析结果显示:女性初潮年龄≥15岁、绝经年龄≤50岁、有2型糖尿病史可能是甲状腺癌的危险因素;多因素分析结果显示:女性绝经年龄≤50岁、有2型糖尿病史是甲状腺癌的危险因素,差异具有统计学意义(P<0.05).结论女性绝经年龄≤50岁、2型糖尿病史是甲状腺癌的危险因素,可通过健康宣教,避免相关危险因素暴露,从而降低甲状腺癌发病率.Objective To investigate the relationship between type 2 diabetes mellitus,female menstrual history and reproductive history and the risk of thyroid cancer,and to provide scientific basis for the early prevention of thyroid cancer.Methods A self-designed questionnaire was used to investigate 202 thyroid cancer patients diagnosed by Zhejiang Hospital of Traditional Chinese Medicine in Hangzhou from 2018 to 2019 and 202 control patients selected by 1:1 matching method.Results The univariate analysis showed that age of menarche≥15 years,age of menopause≤50 years,and history of type 2 diabetes were risk factors for thyroid cancer.The results of multivariate analysis showed that menopausal age≤50 years old and the history of type 2 diabetes were the risk factors for thyroid cancer,and the difference was statistically significant.Conclusion Menopausal age≤50 years and history of type 2 diabetes are risk factors for thyroid cancer.Health education can be carried out to avoid exposure to related risk factors,so as to reduce the incidence of thyroid cancer.

关 键 词：甲状腺癌 危险因素 病例对照研究 

分 类 号：R587.1[医药卫生—内分泌] R736.1[医药卫生—内科学]