不同性别胃癌患者术化前后身体组分分析  

Analysis of Body Composition Before and After Surgery in Patients with Gastric Cancer of Different Genders

作　　者：赵亚子 翟建[1] 赵田英 刘艳 ZHAO Yazi;ZHAI Jian;ZHAO Tianying(Imaging Center,Yijishan Hospital,Wannan Medical College,Wuhu,Anhui Province 241000,P.R.China)

机构地区：[1]皖南医学院弋矶山医院影像中心,安徽芜湖241000

出　　处：《临床放射学杂志》2022年第11期2063-2067,共5页Journal of Clinical Radiology

摘　　要：目的探讨不同性别胃癌患者术化前后身体组分的变化。方法分析34例男性、28例女性胃癌患者术化前与术化后1年以内分别进行腹部CT扫描的结果。采用QCT PRO进行人体成分分析。测定L_(3)中部层面皮下脂肪面积(SFA)、腹内脂肪面积(VFA),并计算L_(3)中部层面总脂肪面积(TFA)及VFA/SFA。测定L_(3)中部层面椎后肌群脂肪面积、椎后肌群肌肉面积,并计算椎后肌群肌肉脂肪浸润程度(MFI)。测定L_(1)、L_(2)骨密度并计算平均骨密度(BMD)进行比较。结果男性患者术化后L_(3)中部层面椎后肌群脂肪面积、椎后肌群肌肉面积、L_(3)中部层面SFA、VFA、TFA及平均BMD均较术化前呈现出下降趋势,差异有统计学意义(P<0.05)。女性患者术化后L_(3)中部层面椎后肌群脂肪面积,L_(3)中部层面皮下脂肪面积、VFA、TFA及平均BMD较术化前均呈现下降趋势,差异具有统计学意义(P<0.05)。男性患者、女性患者术化后L_(3)中部层面椎后肌群MFI及VFA/SFA较术化前差异没有统计学意义(P>0.05)。除此之外,女性患者术化后L_(3)中部层面椎后肌群肌肉面积较术化前差异没有统计学意义(P>0.05)。结论胃癌术化后患者身体组分会不同程度的下降,尤以腹内脂肪面积为著;如能尽早进行干预,可以避免术化后引起的营养不良及肌少症,从而提高患者生活质量。Objective To investigate the changes of body composition in different gender patients with gastric cancer before and after surgery.Methods The results of abdominal CT scan in 34 male and 28 female patients with gastric cancer were analyzed before and within one year after surgery.QCT PRO was used for body composition analysis.Subcutaneous fat area(SFA)and visceral fat area(VFA)at the middle layer of L_(3)were measured,and total fat area(TFA)and visceral fat area(VFA)/subcutaneous fat area(SFA)at the middle layer of L_(3)were calculated.Fat area and muscle area of posterior vertebral muscle group at middle L_(3)level were measured,and MFI degree of posterior vertebral muscle group was calculated.Bone density of L_(1)and L_(2)were measured and the average bone mineral density(BMD)was calculated.All the values were compared.Results Male patients after the operation of L_(3)central level after vertebral muscles fat area,vertebral muscles after muscle area,central L_(3)level subcutaneous fat area(SFA),visceral fat area(VFA),total fat area(TFA)and bone mineral density(BMD)on average,than present a downward trend before the operation,the difference was statistically significant(P<0.05).After surgery,the fat area of posterior vertebral muscle group at middle L_(3)level,subcutaneous fat area,visceral fat area(VFA),total fat area(TFA)and average bone mineral density(BMD)of female patients showed a downward trend compared with that before surgery,with statistical significance(P<0.05).There were no significant differences in MFI of posterior vertebral muscle group at middle L_(3) level and VFA/SFA between male and female patients after surgery compared with before surgery(P>0.05).In addition,there was no statistically significant difference in muscle area of posterior vertebral muscle group at L_(3) middle level in female patients after surgery compared with before surgery(P>0.05).Conclusion After surgery for gastric cancer,the body composition of patients decreased to different degrees,especially the visceral fat area(VFA).

关 键 词：胃癌 定量CT 术化前后身体组分 骨密度 

分 类 号：R735.2[医药卫生—肿瘤]