通天口服液联合尤瑞克林治疗急性脑梗死的疗效  

Study on the therapeutic effect of Tongtian oral liquid combined with urinary kallidinogenase on acute cerebral infarction

作　　者：甘本辉 刘丹 陈龙雯 GAN Benhui;LIU Dan;CHEN Longwen(Department of Neurology,the Affiliated Fengcheng Hospital of Yichun University/Fengcheng People's Hospital,Fengcheng,Jiangxi 331100,China)

机构地区：[1]宜春学院附属丰城医院/丰城市人民医院神经内科,江西丰城331100

出　　处：《现代医药卫生》2023年第4期602-604,共3页Journal of Modern Medicine & Health

摘　　要：目的 观察通天口服液联合尤瑞克林治疗急性脑梗死患者的临床疗效。方法 选取2020年10月至2022年3月该院神经内科收治的118例急性脑梗死住院患者为研究对象,根据治疗方法的不同分为对照组和观察组,各59例。2组均采用常规基础治疗,对照组在此基础上给予尤瑞克林,观察组在对照组基础上给予通天口服液,用药14 d后比较2组美国国立卫生院神经功能缺损评分(NIHSS)、总有效率及不良反应发生情况。结果 2组治疗前NIHSS得分比较,差异无统计学意义(P>0.05)。与治疗前比较,2组治疗后NIHSS得分均有不同程度降低,且观察组低于对照组,差异有统计学意义(P<0.05)。观察组总有效率[93.22%(55/59)]优于对照组[77.97%(46/59)],差异有统计学意义(P<0.05)。对照组未出现明显不良反应,观察组出现腹痛2例、皮疹1例,2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论 通天口服液联合尤瑞克林能有效改善急性脑梗死患者神经功能。Objective To evaluate the clinical efficacy of Tongtian oral liquid combined with urinary kallidinogenase on patients with acute cerebral infarction.Methods A total of 118 cases with acute cerebral infarction admitted to the Department of Neurology of this hospital from October 2020 to March 2022 were selected as the research objects, and were divided into the control group and the observation group according to different treatment methods, with 59 cases in each group.Both groups were given routine basic treatment, and the control group was given urinary kallidinogenase, and the observation group was given Tongtian oral liquid on the basis of the control group.After 14 days of treatment, the National Institutes of Health Stroke Scale(NIHSS) score, total effective rate and adverse reaction of the two groups were compared.Results There was no difference in NIHSS score between the two groups before treatment(P>0.05).Compared with before treatment, the NIHSS score of the two groups decreased in different degrees after treatment, and the observation group was less than the control group, and the differences were statistically significant(P<0.05).The total effective rate of the observation group [93.22%(55/59)] was better than that of the control group [77.97%(46/59)],with statisitical significance(P<0.05).There was no obvious adverse reaction in the control group, but there were two cases of abdominal pain and one case of rash in the observation group.There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Combined use of urinary kallidinogenase and Tongtian oral liquid can effectively improve the neurological function of patients with acute cerebral infarction.

关 键 词：通天口服液 尤瑞克林 急性脑梗死 

分 类 号：R743[医药卫生—神经病学与精神病学]