中心性浆液性脉络膜视网膜病变Henle纤维层频域OCT影像特征  

Features of Henle fiber layer by spectral domain optical coherence tomography in central serous chorioretinopathy

作　　者：刘伟伟[1] 陈文涛 张博 李南 赵超 胡锐[1,2] Liu Weiwei;Chen Wentao;Zhang Bo;Li Nan;Zhao Chao;Hu Rui(Department of Ophthalmology,the Third People's Hospital of Qingdao,Qingdao 266041,China;Department of Ophthalmology of the Affiliated Hospital of Qingdao University,Qingdao 266003)

机构地区：[1]青岛市第三人民医院眼科,青岛266041 [2]青岛大学附属医院眼科,青岛266003

出　　处：《中华实验眼科杂志》2023年第1期35-41,共7页Chinese Journal Of Experimental Ophthalmology

摘　　要：目的观察中心性浆液性脉络膜视网膜病变(CSC)Henle纤维层(HFL)频域光相干断层扫描(SD-OCT)的影像特征。方法采用横断面研究,纳入2017年1月至2021年11月在青岛市第三人民医院眼科确诊的CSC患者35例35眼。其中男23例23眼,女12例12眼;年龄24~60岁,平均(41.14±8.19)岁;病程1 d~6个月。所有患者均应用SD-OCT对黄斑部进行水平单线扫描,分析和总结视网膜下液(SRF)区HFL的影像特征。结果CSC视网膜神经上皮层呈规则圆顶形脱离者26眼,SRF区HFL呈边界1型25眼,占96.15%;呈边界2型7眼,占26.92%;呈完全高反射型17眼,占65.38%。病程≤21 d 21眼,均呈边界1型,部分合并完全高反射型或边界2型;病程>21 d 5眼,均呈完全高反射型,部分合并边界1型或边界2型。其中鼻侧和颞侧脱离区基本对称15眼,6眼为水平位图像,两侧SRF区HFL均呈基本对等的光反射信号;3眼为鼻侧抬高位图像,鼻侧SRF区HFL光反射信号均高于颞侧;6眼为颞侧抬高位图像,颞侧SRF区HFL光反射信号均高于鼻侧。鼻侧和颞侧脱离区不对称11眼,其中3眼为水平位图像,颞侧脱离范围均大于鼻侧,颞侧SRF区HFL光反射信号均高于鼻侧;4眼为鼻侧抬高位图像,3眼颞侧脱离范围大于鼻侧,两侧SRF区HFL呈基本对等的光反射信号,1眼鼻侧脱离范围大于颞侧,鼻侧SRF区HFL光反射信号高于颞侧;4眼为颞侧抬高位图像,3眼鼻侧脱离范围大于颞侧,两侧SRF区HFL呈基本对等的光反射信号,1眼鼻侧脱离范围和高度均大于颞侧,鼻侧SRF区HFL光反射信号高于颞侧。CSC视网膜神经上皮层呈不规则形脱离9眼,SRF区HFL呈边界1型7眼,占77.78%;呈边界2型5眼,占55.56%;呈完全高反射型6眼,占66.67%;呈低反射型4眼,占44.44%;呈模糊型2眼,占22.22%。其中7眼脱离的视网膜神经上皮层走行欠平滑,HFL表现类型随视网膜神经上皮层走向的改变而改变;2眼视网膜神经上皮层脱离低平,抬高侧光反射信号略低于压低侧�Objective To observe the features of Henle fiber layer(HFL)in eyes with central serous chorioretinopathy(CSC)using spectral domain optical coherence tomography(SD-OCT).Methods A cross-sectional study was conducted.Thirty-five CSC patients(35 eyes)treated in the Third People's Hospital of Qingdao from January 2017 to November 2021 were enrolled.The subjects included 23 males(23 eyes)and 12 females(12 eyes),aged 24 to 60 years old,with an average age of(41.14±8.19)years,and had a CSC duration ranged from 1 day to 6 months.SD-OCT was performed on all eyes with a line scan through the central fovea horizontally.The features of HFL over subretinal fluid(SRF)area were analyzed and summarized.The study protocol adhered to the Declaration of Helsinki and was approved by the Ethics Committee of the Third People's Hospital of Qingdao(No.2022Y0403001).Results In 26 eyes with regular dome-shaped neurosensory retinal detachment,HFL appeared to be delimited type 1 in 25 eyes,accounting for 96.15%,delimited type 2 in 7 eyes,accounting for 26.92%,bright in 17 eyes,accounting for 65.38%over SRF area.In 21 eyes with CSC duration≤21 days,HFL all showed delimited type 1 and some presented bright or delimited type 2 at the same time.In 5 eyes with CSC duration>21 days,HFL all showed bright and some were delimited type 1 or delimited type 2 in the meantime.In 15 eyes with symmetrical nasal and temporal retinal detachment,HFL showed symmetrical reflectivity over SRF area in horizontal OCT images in 6 eyes,and showed brighter reflectivity over nasal SRF in nasal elevated OCT images in 3 eyes and over temporal SRF in temporal elevated OCT images in 6 eyes.In 11 eyes with asymmetrical nasal and temporal retinal detachment,HFL showed brighter reflectivity over temporal SRF with larger retinal detachment range on temporal side in horizontal OCT images in 3 eyes.Of the 4 eyes with nasal elevated OCT images,the retinal detachment range was larger on temporal side and HFL showed symmetrical reflectivity over SRF area in 3 eyes,and HFL was b

关 键 词：中心性浆液性脉络膜视网膜病变 频域光相干断层扫描 Henle纤维层 

分 类 号：R774.1[医药卫生—眼科]