慢性胰腺炎患者营养不良的发病原因及诊治进展  

Pathogenesis,diagnosis,and treatment of malnutrition in patients with chronic pancreatitis

作　　者：曾祥鹏 曾静慧 王蓉[1] 王雯[1] Xiang-Peng Zeng;Jing-Hui Zeng;Rong Wang;Wen Wang(Department of Gastroenterology,900th Hospital of Joint Logistics Support Force,Fuzhou 350001,Fujian Province,China)

机构地区：[1]中国人民解放军联勤保障部队第九OO医院消化内科,福建省福州市350001

出　　处：《世界华人消化杂志》2023年第3期92-97,共6页World Chinese Journal of Digestology

基　　金：国家自然科学基金项目,No.82100687。

摘　　要：慢性胰腺炎(chronic pancreatitis,CP)是一种持续、进展性的胰腺炎症性疾病,营养不良是CP患者较常见的临床表现,主要是由胰腺外分泌功能不全引起,也可能与胰腺内分泌功能不全、生活习惯改变有关.目前仍缺乏CP患者营养不良的诊断金标准,临床医生应通过人体测量参数、检验参数、影像学诊断、胰腺外分泌功能检测等方面进行综合评估,早期发现CP患者的营养不良,及时采取干预措施,包括改善饮食及生活习惯、肠内/肠外营养、胰酶替代疗法、抑酸药辅助治疗、调节肠道菌群、中医中药等,必要时采用内镜和外科手术治疗.Chronic pancreatitis(CP)is a persistent and progressive pancreatic inflammatory disease.Malnutrition is a common clinical manifestation in CP patients,which is mainly caused by pancreatic exocrine insufficiency but may also be related to pancreatic endocrine insufficiency and changes of living habit.At present,there is still a lack of gold standard for the diagnosis of malnutrition in patients with CP.Clinicians should comprehensively evaluate such patients through anthropometric parameters,test parameters,imaging diagnosis,pancreatic exocrine function detection,etc.,detect malnutrition early,and take timely intervention measures,including improving diet and living habits,enteral/parenteral nutrition,pancreatic enzyme replacement therapy,acid suppressant adjuvant therapy,regulating intestinal flora,and administration of Chinese medicine.And endoscopic and surgical treatment should be used when necessary.

关 键 词：慢性胰腺炎 营养不良 胰腺外分泌功能不全 胰酶替代治疗 

分 类 号：R576[医药卫生—消化系统]