结直肠癌患者围手术期静脉血栓栓塞症预防及治疗进展  

Prevention and treatment of perioperative venous thromboembolism in colorectal cancer patients

作　　者：韦奇 姚宏伟[1] 张忠涛[1] Wei Qi;Yao Hongwei;Zhang Zhongtao(Department of General Surgery,Beijing Friendship Hospital,Capital Medical University,Bejing 100050,China)

机构地区：[1]首都医科大学附属北京友谊医院普外科,北京100050

出　　处：《国际外科学杂志》2023年第1期61-67,共7页International Journal of Surgery

基　　金：国家科技支撑计划课题(2015BAI13B09);国家重点研发计划资助(2017YFC0110904);首都卫生发展科研重点项目(首发2018-1-1111);首都医科大学结直肠肿瘤临床诊疗与研究中心基金项目(1192070313);首都医科大学附属北京友谊医院科研启动基金(YYQDKT2016-5)。

摘　　要：静脉血栓栓塞症(VTE)是恶性肿瘤患者围手术期常见的并发症。结直肠癌肿瘤本身及手术治疗等因素均可增加患者围手术期VTE的风险。近年来,随着加速康复外科理念的发展,肿瘤相关静脉血栓认识的加深,肿瘤相关VTE风险评估、预防与治疗策略等方面取得了重大进展。本文将对结直肠癌相关VTE的发病机制、危险因素及风险评估、预防和治疗策略进行综述,以期为结直肠癌相关VTE的规范管理和未来研究提供循证医学证据和研究思路。Venous thromboembolism(VTE)is a common perioperative complication in patients with malignant tumors.Factors such as colorectal cancer itself and surgical treatment can increase the risk of perioperative VTE.In recent years,with the development of the concept of enhanced recovery after surgery,the understanding of cancer-associated venous thrombosis has deepened,and significant progress has been made in the risk assessment,prevention and treatment strategies of cancer-associated VTE.This article will review the pathogenesis,risk factors,risk assessment,prevention and treatment strategies of colorectal cancer-associated VTE,in order to provide evidence-based medical basis and research ideas for the standardized management and future research of colorectal cancer-associated VTE.

关 键 词：血栓形成 肺栓塞 治疗应用 静脉血栓栓塞症 深静脉血栓形成 

分 类 号：R735.34[医药卫生—肿瘤]