天然药物苏木对人工脱矿釉质龋的再矿化作用  

Remineralization Effect of Caesalpinia Sappan L. on Artificial Demineralization of Enamel Caries

作　　者：李茹芳 李秋艳 崔霞 赵霞 王丽梅 蓝海 LI Rufang;LI Qiuyan;CUI Xia;ZHAO Xia;WANG Limei;LAN hai(School of Pharmacy,Dali University,Dali Yunnan 671000;Dept.of Stomatology,Dali Bai Autonomous Prefecture People’s Hospital,Dali Yunnan 671000,China)

机构地区：[1]大理大学药学院,云南大理671000 [2]大理白族自治州人民医院口腔科,云南大理671000

出　　处：《昆明医科大学学报》2023年第2期23-26,共4页Journal of Kunming Medical University

基　　金：国家自然科学基金资助项目(81260512);大理大学科研发展基金资助项目(FZ2023YB009)。

摘　　要：目的 观察苏木乙醇提取物、乙酸乙酯、正丁醇、水萃取部位对人工脱矿釉质龋的作用。方法 将牛切牙制成人工脱矿釉质龋后,测定苏木乙醇提取物和不同萃取部位对牛切牙釉质表面显微硬度的影响,扫描电镜观察各实验组对釉质龋表面形态的影响。结果 乙醇提取物和各萃取部位都有提高釉质龋表面硬度的作用,其中水萃取部位对釉质硬度恢复效果最好,硬度恢复率达到66.9%(P <0.05)。扫描电镜观察到各实验组的釉质龋表面覆盖有大量颗粒状沉积物。结论 苏木乙醇提取物及各萃取部位对人工脱矿釉质龋均有再矿化作用。Objective To observe the effects of Caesalpinia Sappan L. ethanol extract,ethyl acetate,nbutanol and water extract on artificial demineralization enamel caries. Methods Bovine incisors were made into artificial demineralized enamel caries. The effects of Caesalpinia Sappan L. ethanol extract and different extraction parts on the microhardness of enamel surface of bovine incisors were determined. The effects of different experimental groups on the surface morphology of enamel caries were observed by scanning electron microscope. Results Both ethanol extract and all extracts improved the surface hardness of enamel caries,and water extract had the best effect on enamel hardness recovery,with the hardness recovery rate reaching 66.9%(P < 0.05). The surface of enamel caries in each experimental group was covered with a large amount of granular sediments. Conclusion The ethanol extract of Caesalpinia Sappan L. and its extracts have the effect of remineralization on artificial demineralization of enamel caries.

关 键 词：苏木 人工釉质龋 显微硬度 扫描电镜 

分 类 号：R285.5[医药卫生—中药学]