单/双脉冲经颅磁刺激检测皮质兴奋性在癫痫的应用及前景  

Application and Prospect of Single/paired Pulse Transcranial Magnetic Stimulation in Detecting Cortical Excitability in Epilepsy Patients

作　　者：周营营 吴辉婷 黄珊珊[1] 朱遂强[1] ZHOU Ying-ying;WU Hui-ting;HUANG Shan-shan;ZHU Sui-qiang(Department of Neurology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China)

机构地区：[1]华中科技大学同济医学院附属同济医院神经内科,武汉430030

出　　处：《神经损伤与功能重建》2023年第2期92-95,共4页Neural Injury and Functional Reconstruction

基　　金：湖北省技术创新专项(No.2019ACA132);中央高校基本科研业务费专项资金资助(No.2019kfyXK JC075)。

摘　　要：经颅磁刺激可作为一项无创的、非侵入性的测量大脑皮质兴奋性的神经生理技术,近年来广泛应用于研究癫痫的病因及耐药机制等。本文对单/双脉冲经颅磁刺激在癫痫患者皮质兴奋性检测中的应用进行综述,总结此项检测获得的参数在癫痫病因探索、癫痫分类及用药指导等方面的作用及前景。Transcranial magnetic stimulation(TMS), as a non-invasive neurophysiological technique to measure cerebral cortical excitability, has been widely used to study the etiology and drug resistance mechanism of epilepsy in recent years. This article reviews the application of single/paired pulse TMS in detection of cortical excitability in patients with epilepsy, and summarizes the role of TMS in exploration of causes, classification and medication guidance of epilepsy.

关 键 词：经颅磁刺激 癫痫 皮质兴奋性 

分 类 号：R741[医药卫生—神经病学与精神病学] R741.04[医药卫生—临床医学] R741.05R742.1