超声引导细针穿刺及超声造影检查在甲状腺癌早期诊断中的联合应用价值  

Combined application valueof ultrasound-guided fine needle aspiration and contrastenhanced ultrasonography in theearly diagnosis of thyroid cancer

作　　者：刘英 杨加惠 郭磊磊 胡礼桂 曾敏 赵仁军[2] LIU Ying;YANG Jiahui;GUO Leilei;HU Ligui;ZENG Min;ZHAO Renjun(Department of Ultrasound,Meishan Cardioand Cerebrovascular Disease Hospital,Meishan,Sichuan 620010,China;Departmentof Ultrasound,The Third Affiliated Hospital of Yan’an University,Xianyang,Shaanxi 712000,China)

机构地区：[1]四川省眉山心脑血管病医院超声科,620010 [2]延安大学第三附属医院超声科,陕西咸阳712000

出　　处：《重庆医学》2022年第S02期58-61,共4页Chongqing medicine

摘　　要：目的探讨超声引导细针穿刺及超声造影检查在甲状腺癌早期诊断中的联合应用价值。方法选取2019年10月至2021年11月收治的甲状腺癌患者73例设为研究组,另选取同期收治的甲状腺良性结节患者73例设为对照组。两组患者均分别接受超声引导细针穿刺及超声造影检查,统计分析超声引导细针穿刺、超声造影检查对甲状腺癌的单独及联合检测的诊断情况、诊断效能(灵敏度、特异性、准确性、阴性预测值、阳性预测值)等。结果联合检测诊断的灵敏度、阳性预测值均明显高于超声造影,差异均有统计学意义(P<0.05);联合检测诊断的特异性、准确性、阴性预测值与超声造影比较,差异均无统计学意义(P>0.05)。联合检测诊断的灵敏度、特异性、准确性、阴性预测值、阳性预测值与超声引导细针穿刺比较,差异均无统计学意义(P>0.05)。超声引导细针穿刺诊断的灵敏度明显高于超声造影,差异有统计学意义(P<0.05);超声引导细针穿刺诊断的特异性、准确性、阴性预测值、阳性预测值与超声造影比较,差异均无统计学意义(P>0.05)。结论联合采取超声引导细针穿刺及超声造影对甲状腺癌进行诊断可提升诊断的灵敏度及阳性预测值,最大限度地减少漏、误诊,值得推广应用。Objective To explore the combined value of ultrasound-guided fine needle aspiration and contrast-enhanced ultrasonography in the early diagnosis of thyroid cancer.Methods 73 patients with thyroid cancer in our hospital from October 2019 to November 2021 were selected as the study group,and 73 patients with benign thyroid nodules in the same period were selected as the control group.The subjects of the two groups received ultrasound-guided fine needle puncture and contrast-enhanced ultrasonography respectively.The individual and combined diagnosis and diagnostic efficacy(sensitivity,specificity,accuracy,negative predictive value and positive predictive value)of ultrasound-guided fine needle puncture and contrast-enhanced ultrasonography for thyroid cancer were statistically analyzed.Results 70 cases of thyroid cancer and 63 cases of benign thyroid nodules were detected by fine needle puncture,61 cases of thyroid cancer and 66 cases of thyroid nodules were detected by contrast-enhanced ultrasound,72 cases of thyroid cancer and 64 cases of thyroid nodules were detected by combined diagnosis;The sensitivity(98.63%)and positive predictive value(98.46%)of combined diagnosis were higher than those of contrast-enhanced ultrasound(83.56%and 84.62%).The difference was statistically significant(P<0.05).There was no significant difference between the specificity(89.04%),accuracy(93.15%)and negative predictive value(88.89%)of combined diagnosis and the control group.ConclusionThe combination of ultrasound-guided fine-needle aspiration and contrast-enhanced ultrasound in the diagnosis of thyroid cancer can improve the diagnostic sensitivity and positive predictive value,minimize missed diagnosisand misdiagnosis,and is worthy of popularization and application.

关 键 词：甲状腺癌 超声内镜引导细针穿刺活检术 超声造影 

分 类 号：R736.1[医药卫生—肿瘤]