骨髓纤维化的中西医治疗研究进展  

Research Progress in the Treatment of Myelofibrosis by Integrated Chinese and Western Medicine

作　　者：何婕敏 孙雪梅[2] HE Jie-min;SUN Xue-mei(The First Clinical Medical School of Nanjing University of Chinese Medicine,Nanjing 210029 Jiangsu,China;Jiangsu Provincial Hospital of Traditional Chinese Medicine,Nanjing 210029 Jiangsu,China)

机构地区：[1]南京中医药大学第一临床医学院,江苏南京210029 [2]江苏省中医院,江苏南京210029

出　　处：《中医肿瘤学杂志》2023年第1期65-71,共7页Journal of Oncology in Chinese Medicine

基　　金：江苏省中医院项目(编号:y2021rc05)。

摘　　要：骨髓纤维化(myelofibrosis,MF)包括原发和继发,是一种源于造血干细胞的克隆性增殖的血液系统疾病。目前异基因造血干细胞移植仍然是唯一有可能使患者获得治愈或显著延长生存期的方法。MF的治疗往往基于患者的临床需要,以缓解疾病相关症状、预防并发症、诱导长期完全缓解为目标。本文对近年来MF发病机制和治疗的研究进展做一综述。Myelofibrosis(MF)is a myeloproliferative neoplasm originating from the clonal proliferation of a hematopoietic stem/progenitor cell.MF can be classified into the primary MF and secondary MF.Till now,allogeneic hematopoietic cell transplantation is the only therapy that is capable of prolonging survival or curing the patients of MF.The treatment of MF is often based on the wishes of patients,and aims to relieve disease associated symptoms,prevent the occurrence of complications,and induce long-term complete remission.This paper reviewed the pathogenesis and treatment of MF in recent years.

关 键 词：骨髓纤维化 发病机制 治疗 

分 类 号：R733.3[医药卫生—肿瘤] R273[医药卫生—临床医学]