Early postsurgical lethal outcome due to splenic littoral cell angioma:A case report  

作　　者：Fan Jia Han Lin Yi-Long Li Jin-Ling Zhang Liang Tang Peng-Tian Lu Yu-Qing Wang Yi-Feng Cui Xiu-Hua Yang Zhao-Yang Lu 

机构地区：[1]Department of Abdominal Ultrasound,First Affiliated Hospital of Harbin Medical University,Harbin 150001,Heilongjiang Province,China [2]Department of Hepatic Surgery,Key Laboratory of Hepatosplenic Surgery,Ministry of Education,The First Affiliated Hospital of Harbin Medical University,Harbin 150001,Heilongjiang Province,China [3]Department of Pancreatic and Biliary Surgery,Key Laboratory of Hepatosplenic Surgery,Ministry of Education,The First Affiliated Hospital of Harbin Medical University,Harbin 150001,Heilongjiang Province,China [4]Department of Radiology and Nuclear Medicine,The First Affiliated Hospital of Harbin Medical University,Harbin 150001,Heilongjiang Province,China [5]Department of Pathology,The First Affiliated Hospital of Harbin Medical University,Harbin 150001,Heilongjiang Province,China [6]Department of Hematopathology,First Affiliated Hospital of Harbin Medical University,Harbin 150001,Heilongjiang Province,China

出　　处：《World Journal of Clinical Cases》2023年第5期1188-1197,共10页世界临床病例杂志

基　　金：Supported by the National Natural Science Foundation of China,No.81972230;Hubei Technological Innovation Special Fund(CN),No.CXPJJH11800004-004,No.CXPJJH122002-063,and No.CXPJJH122002-092;University Nursing Program for Young Scholar with Creative Talents in Heilongjiang Province,No.UNPYSCT-2017064;Postdoctoral Foundation of Hei Long Jiang Province,No.LBH-Z20196 and No.LBH-Z20178;China Postdoctoral Science Foundation,No.2021MD703835;Wu Jie-Ping Medical Foundation,No.320.6750.2021-23-22;Open Fund of Key Laboratory of Hepatosplenic Surgery,Ministery of Education,Harbin,China,No.GPKF202204;Excellent Youth Science Fund of the First Hopital of Harbin Medical University,No.2021Y01;Scientifc Foundation of the First Afliated Hospital of Harbin Medical University,No.2021B03。

摘　　要：BACKGROUND Littoral cell angioma(LCA)is a rare benign vascular tumor of the spleen.Given its rarity,standard diagnostic and therapeutic recommendations have yet to be developed for reported cases.Splenectomy is the only method of obtaining a pathological diagnosis and providing treatment to obtain a favorable prognosis.CASE SUMMARY A 33-year-old female presented with abdominal pain for one month.Computed tomography and ultrasound revealed splenomegaly with multiple lesions and two accessory spleens.The patient underwent laparoscopic total splenectomy and accessory splenectomy,and splenic LCA was confirmed by pathology.Four months after surgery,the patient presented with acute liver failure,was readmitted,rapidly progressed to multiple organ dysfunction syndrome and died.CONCLUSION Preoperative diagnosis of LCA is challenging.We systematically reviewed online databases to identify the relevant literature and found a close relationship between malignancy and immunodysregulation.When a patient suffers from both splenic tumors and malignancy or immune-related disease,LCA is possible.Due to potential malignancy,total splenectomy(including accessory spleen)and regular follow-up after surgery are recommended.If LCA is diagnosed after surgery,a comprehensive postoperative examination is needed.

关 键 词：Littoral cell angioma Imaging features MALIGNANCY Immunodysregulation Treatment Case report 

分 类 号：R733.2[医药卫生—肿瘤]