Transverse myelitis caused by herpes zoster following COVID-19 vaccination:A case report  

作　　者：Su-Yeon Cho Bo-Hyun Jang Jun-Won Seo Suk-Whee Kim Kyung-Joon Lim Hyun-Young Lee Dong-Joon Kim 

机构地区：[1]Department of Anesthesiology and Pain Medicine,Chosun University Hospital,Gwangju 61453,South Korea [2]Department of Internal Medicine,Chosun University,College of Medicine,Gwangju 61453,South Korea [3]Department of Anesthesiology and Pain Medicine,Chosun University,College of Medicine,Gwangju 61453,South Korea

出　　处：《World Journal of Clinical Cases》2023年第6期1419-1425,共7页世界临床病例杂志

基　　金：Supported by Research fund from Chosun University Hospital,2022.

摘　　要：BACKGROUND Transverse myelitis(TM)is characterized by sudden lower extremity progressive weakness and sensory impairment,and most patients have a history of advanced viral infection symptoms.A variety of disorders can cause TM in association with viral or nonviral infection,vascular,neoplasia,collagen vascular,and iatrogenic,such as vaccination.Vaccination has become common through the global implementation against coronavirus disease 2019(COVID-19)and reported complications like herpes zoster(HZ)activation has increased.CASE SUMMARY This is a 68-year-old woman who developed multiple pustules and scabs at the T6-T9 dermatome site 1 wk after vaccination with the COVID-19 vaccine(Oxford/AstraZeneca([ChAdOx1S{recombinant}]).The patient had a paraplegia aggravation 3 wk after HZ symptoms started.Spinal magnetic resonance imaging(MRI)showed transverse myelitis at the T6–T9 Level.Treatment was acyclovir with steroids combined with physical therapy.Her neurological function was slowly restored by Day 17.CONCLUSION HZ developed after COVID-19 vaccination,which may lead to more severe complications.Therefore,HZ treatment itself should not be delayed.If neurological complications worsen after appropriate management,an immediate diagnostic procedure,such as magnetic resonance imaging and laboratory tests,will start and should treat the neurological complications.

关 键 词：Herpes zoster Transverse myelitis PARAPLEGIA COVID-19 VACCINATION Case report 

分 类 号：R744.3[医药卫生—神经病学与精神病学] R752.12[医药卫生—临床医学]