Upper gastrointestinal bleeding as an unusual manifestation of localized Ménétrier’s disease with an underlying lipoma:A case report  

作　　者：Michal Kmiecik Aleksandra Walczak Pawel Samborski Jacek Paszkowski Agnieszka Dobrowolska Jacek Karczewski Ewelina Swora-Cwynar 

机构地区：[1]Department of Gastroenterology,Nutrition and Internal Medicine,Poznan University of Medical Sciences,Poznan 60-355,Poland [2]Department of Clinical Pathology,Poznan University of Medical Sciences,Poznan 60-355,Poland [3]Department of General&Endocrine Surgery,and Gastroenterological Oncology,Poznan University of Medical Sciences,Poznan 60-355,Poland

出　　处：《World Journal of Gastrointestinal Endoscopy》2023年第1期10-18,共9页世界胃肠内镜杂志（英文版）（电子版）

摘　　要：BACKGROUND Ménétrier’s disease is a rare condition characterized by enlarged gastric folds,usually located in the whole body and fundus of the stomach.This report presents an unusual case of localized Ménétrier’s disease elevated by a submucosal lipoma and thus looking like a polypoid mass and causing an episode of upper gastrointestinal bleeding.The mass was successfully removed with endoscopic submucosal dissection.CASE SUMMARY Esophagogastroduodenoscopy was performed on a 76-year-old male patient after an episode of upper gastrointestinal bleeding,manifesting as fatigue and melena.A large polypoid mass(4 cm×1 cm)with enlarged mucosal folds was found in the body of the stomach,between the lesser curvature and posterior wall.A small ulcer at the distal end of the mass was identified as the source of the bleeding.Biopsy was negative for neoplasia.Computed tomography showed a submucosal lesion beneath the affected mucosa,most likely a lipoma.The mass was removed en bloc with tunneling endoscopic submucosal dissection.Final pathology determined that the mass included Ménétrier’s disease and a submucosal lipoma.The patient was scheduled for follow-up esophagogastroduodenoscopy.CONCLUSION Localized Ménétrier’s disease can coexist with a submucosal lipoma creating a polypoid mass with risk of bleeding.

关 键 词：Ménétrier’s disease Submucosal lipoma Gastrointestinal hemorrhage Endoscopic submucosal dissection Submucosal tunneling endoscopic resection Case report 

分 类 号：R573[医药卫生—消化系统]