Liver involvement in patients with COVID-19 infection:A comprehensive overview of diagnostic imaging features  

作　　者：Davide Ippolito Cesare Maino Federica Vernuccio Roberto Cannella Riccardo Inchingolo Michele Dezio Riccardo Faletti Pietro Andrea Bonaffini Marco Gatti Sandro Sironi 

机构地区：[1]Milano Bicocca School of Medicine and Surgery,Milano 20126,Italy [2]Fondazione IRCCS San Gerardo dei Tintori,Monza 20900,Italy [3]Institute of Radiology(DIMED),University Hospital of Padova,Padova 35128,Italy [4]Section of Radiology-Department of Biomedicine,Neuroscience and Advanced Diagnostics(BiND),University of Palermo,Palermo 90127,Italy [5]Department of Health Promotion,Mother and Child Care,Internal Medicine and Medical Specialties(PROMISE),University of Palermo,Palermo 90127,Italy [6]Division of Interventional Radiology,Department of Radiology,Madonna delle Grazie Hospital,Matera 75100,Italy [7]Department of Surgical Sciences,University of Turin,Turin 10126,Italy [8]Department of Diagnostic Radiology,Papa Giovanni XXIII Hospital,Bergamo 24127,Italy [9]Department of Diagnostic Radiology,University of Turin,Turin 10126,Italy

出　　处：《World Journal of Gastroenterology》2023年第5期834-850,共17页世界胃肠病学杂志（英文版）

摘　　要：During the first wave of the pandemic,coronavirus disease 2019(COVID-19)infection has been considered mainly as a pulmonary infection.However,different clinical and radiological manifestations were observed over time,including involvement of abdominal organs.Nowadays,the liver is considered one of the main affected abdominal organs.Hepatic involvement may be caused by either a direct damage by the virus or an indirect damage related to COVID-19 induced thrombosis or to the use of different drugs.After clinical assessment,radiology plays a key role in the evaluation of liver involvement.Ultrasonography(US),computed tomography(CT)and magnetic resonance imaging(MRI)may be used to evaluate liver involvement.US is widely available and it is considered the first-line technique to assess liver involvement in COVID-19 infection,in particular liver steatosis and portal-vein thrombosis.CT and MRI are used as second-and third-line techniques,respectively,considering their higher sensitivity and specificity compared to US for assessment of both parenchyma and vascularization.This review aims to the spectrum of COVID-19 liver involvement and the most common imaging features of COVID-19 liver damage.

关 键 词：Liver Fatty liver HEPATOMEGALY Hepatic infarction Liver diseases Liver failure Biliary tract diseases COVID-19 SARS-CoV-2 INFECTION X-Ray computed tomography Magnetic resonance imaging ULTRASONOGRAPHY ADULTS PEDIATRICS 

分 类 号：R563.1[医药卫生—呼吸系统]