调胃颗粒联合揿针治疗肝郁脾虚型小儿肠系膜淋巴结炎的临床观察  

Clinical Observation of Tiaowei Granules Combined with Thumb-Tack Needling for Subcutaeous Embedding in the Treatment of Mesenteric Lymphadenitis with Liver Stagnation and Spleen Deficiency Syndrome in Children

作　　者：张琳琳 崔文卓 刘婷婷 张晓伟 ZHANG Lin-Lin;CUI Wen-Zhuo;LIU Ting-Ting;ZHANG Xiao-Wei(Hebei Shijiazhuang Hospital of Traditional Chinese Medicine,Shijiazhuang 050000 Hebei,China)

机构地区：[1]河北省石家庄市中医院,河北石家庄050000

出　　处：《广州中医药大学学报》2023年第1期124-130,共7页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：河北省中医药管理局中医药类科研计划资助项目(编号:2022172)。

摘　　要：【目的】观察调胃颗粒联合揿针治疗肝郁脾虚型小儿肠系膜淋巴结炎的临床疗效。【方法】将60例肝郁脾虚型肠系膜淋巴结炎患儿随机分为观察组和对照组,每组30例。观察组给予调胃颗粒口服联合揿针疗法治疗,对照组给予健康宣教及双歧杆菌三联活菌肠溶胶囊治疗。15 d为1个疗程。治疗15 d后,评价2组临床疗效,观察2组患儿治疗前后中医证候积分的变化情况,以及肠系膜淋巴结大小的变化情况。比较2组患儿治疗后腹痛缓解时间、腹痛消失时间的情况。并比较2组患儿的复发率及不良反应的发生情况。【结果】(1)研究过程中,观察组失访2例,对照组失访1例。最终观察组28例、对照组29例纳入疗效统计。(2)观察组总有效率为96.43%(27/28),对照组为79.31%(23/29)。观察组疗效优于对照组,差异有统计学意义(P<0.05)。(3)治疗后,2组患儿中医证候积分包括腹痛、腹胀、食欲、食量、便秘积分均较治疗前明显降低(P<0.01),且观察组中医证候积分降低明显优于对照组,差异均有统计学意义(P<0.01)。(4)治疗后,2组患儿的肠系膜淋巴结纵径、横径均较治疗前明显缩小(P<0.05),且观察组对肠系膜淋巴结纵径的缩小作用明显优于对照组,差异有统计学意义(P<0.01)。(5)治疗后,观察组腹痛缓解时间、腹痛症状完全消失时间均短于对照组,差异均有统计学意义(P<0.05)。(6)治疗结束1个月后随访,观察组复发率为7.14%(2/28),对照组为41.38%(12/29),观察组的复发率明显低于对照组,差异有统计学意义(P<0.05)。(7)2组患儿治疗前后肝、肾功能均未见明显异常,观察组与对照组均无明显不良反应情况发生。【结论】调胃颗粒联合揿针治疗肝郁脾虚型小儿肠系膜淋巴结炎,能明显改善患儿临床症状,有效缩小淋巴结,疗效显著。Objective To observe the clinical efficacy of Tiaowei Granules combined with thumb-tack needling for subcutaeous embedding in the treatment of pediatric mesenteric lymphadenitis with liver stagnation and spleen deficiency syndrome.Methods Sixty cases of children with liver stagnation and spleen deficiency syndrome of pediatric mesenteric lymphadenitis were randomly divided into the observation group and the control group,with30 cases in each group.In the observation group,the children were treated with oral use of Tiaowei Granules combined with thumb-tack needling for subcutaeous embedding therapy,while the children in the control group were treated with health education and Bifidobacterium Triplex Intestinal Capsules.One treatment course was15 days.After 15 days of treatment,the clinical efficacy of the two groups was evaluated,and the changes in the traditional Chinese medicine(TCM)syndrome score and the changes in the size of mesenteric lymphadenitis were observed in the two groups before and after treatment.The time to relief of abdominal pain and the time to disappearance of abdominal pain after treatment were compared between the two groups.The recurrence rate and the incidence of adverse reactions in the two groups were also compared.Results(1)During the study,2 cases were lost from the observation group and one case was lost from the control group.Finally,28 cases in the observation group and 29 cases in the control group were included in the efficacy statistics.(2)The total effective rate of the observation group was 96.43%(27/28),and that of the control group was 79.31%(23/29).The efficacy of the observation group was superior to that of the control group,the difference being statistically significant(P<0.05).(3)After treatment,the TCM syndrome scores including abdominal pain,abdominal distension,appetite,food intake and constipation scores of the children in both groups were significantly decreased compared with those before treatment(P<0.01),and the TCM syndrome scores of the observation group were si

关 键 词：揿针 调胃颗粒 小儿肠系膜淋巴结炎 肝郁脾虚型 临床观察 

分 类 号：R246.9[医药卫生—针灸推拿学]