结合快速独立成分分析算法和卷积神经网络的胎儿心电信号提取与分析方法  

Fetal electrocardiogram signal extraction and analysis method combining fast independent component analysis algorithm and convolutional neural network

作　　者：杨玉瑶 郝婧宇 吴水才[1] YANG Yuyao;HAO Jingyu;WU Shuicai(Department of Biomedical Engineering,Beijing University of Technology,Beijing 100124,P.R.China)

机构地区：[1]北京工业大学生物医学工程系,北京100124

出　　处：《生物医学工程学杂志》2023年第1期51-59,共9页Journal of Biomedical Engineering

摘　　要：胎儿心电信号为胎儿异常情况的早期诊断和干预提供了重要的临床信息,本文提出一种胎儿心电信号提取与分析的新方法。首先,将改进的快速独立成分分析(FastICA)法和奇异值分解(SVD)算法结合,来提取高质量胎儿心电信号并解决波形缺失问题。其次,运用一种新的卷积神经网络(CNN)模型识别胎儿心电信号QRS复合波,并有效解决波形重叠问题。最终,实现胎儿心电信号的高质量提取与胎儿QRS复合波的智能识别。以复杂生理信号研究资源网2013年心脏病学计算挑战赛(PhysioNet2013)数据库资料对本文所提方法进行验证,结果表明该提取算法平均灵敏度与阳性预测值为98.21%和99.52%;QRS复合波识别算法平均灵敏度与阳性预测值为94.14%和95.80%,相较于其他研究成果均有较好的提升。综上,本文提出的算法与模型具有一定的实践意义,今后或可为临床医学决策提供理论依据。Fetal electrocardiogram(ECG) signals provide important clinical information for early diagnosis and intervention of fetal abnormalities. In this paper, we propose a new method for fetal ECG signal extraction and analysis.Firstly, an improved fast independent component analysis method and singular value decomposition algorithm are combined to extract high-quality fetal ECG signals and solve the waveform missing problem. Secondly, a novel convolutional neural network model is applied to identify the QRS complex waves of fetal ECG signals and effectively solve the waveform overlap problem. Finally, high quality extraction of fetal ECG signals and intelligent recognition of fetal QRS complex waves are achieved. The method proposed in this paper was validated with the data from the PhysioNet computing in cardiology challenge 2013 database of the Complex Physiological Signals Research Resource Network. The results show that the average sensitivity and positive prediction values of the extraction algorithm are 98.21% and 99.52%,respectively, and the average sensitivity and positive prediction values of the QRS complex waves recognition algorithm are 94.14% and 95.80%, respectively, which are better than those of other research results. In conclusion, the algorithm and model proposed in this paper have some practical significance and may provide a theoretical basis for clinical medical decision making in the future.

关 键 词：胎儿心电信号 QRS复合波 快速独立成分分析 奇异值分解 卷积神经网络 

分 类 号：R714.5[医药卫生—妇产科学]