维生素C有效期的快速测定  

Rapid Determination of Vitamin C Validity

作　　者：王晓辉[1] 史小琴[1] 庄文昌[1] 董黎明[1] 李靖[1] 蔡可迎[1] WANG Xiaohui;SHI Xiaoqin;ZHUANG Wenchang;DONG Liming;LI Jing;CAI Keying(School of Materials and Chemical Engineering,Xuzhou University of Technology,Xuzhou 221111)

机构地区：[1]徐州工程学院材料与化学工程学院,徐州221111

出　　处：《食品工业》2023年第1期317-319,共3页The Food Industry

基　　金：江苏省现代教育技术研究课题(项目编号:2019-R-79391);徐州工程学院高等教育科学研究课题(项目编号:YGJ2049)。

摘　　要：在经典加速法基础上,以维生素C水溶液为研究对象,针对复杂反应体系,采用导数光谱法克服多组分紫外分析中吸收峰的重叠,测定维生素C的含量。结果表明,以导数光谱为依据,糠醛类物质在维生素C的最大紫外吸收波长266 nm处的吸光度对维生素C定量测定干扰得到消除,确定试验温度30~40℃。采用经典加速法测定维生素C的分解速率常数,根据Arrhenius公式,计算维生素C在25℃时的有效期约1.1 h。试验方法简单、准确、节约、高效,所建的降解动力学理论模型理想、可靠,结果与实际吻合良好。Based on the classical acceleration method, taking vitamin C aqueous solution as the research object, aiming at the complex reaction system, derivative spectroscopy was used to overcome the overlap of absorption peak in multicomponent UV analysis and to determine the content of vitamin C. The experimental results showed that based on the derivative spectrum,the interference of the background absorption of furfural substances at the maximum ultraviolet absorption wavelength of vitamin C at 266 nm on the quantitative determination of vitamin C was eliminated, and the experimental temperature was determined to be 30-40 ℃. The decomposition rate constant of vitamin C was determined by classical acceleration method.According to Arrhenius formula, the validity period of vitamin C at 25 ℃ was calculated to be about 1.1 h. The experimental method was simple, accurate, economical and efficient. The theoretical model of degradation kinetics was ideal and reliable,and the results were in good agreement with the practice.

关 键 词：维生素C 药物有效期 导数光谱法 紫外分光光度法 化学动力学 

分 类 号：O657.3[理学—分析化学] TQ466.3[理学—化学]