Actin polymerization induces mitochondrial distribution during collective cell migration  

作　　者：Chen Qu Yating Kan Hui Zuo Mengqi Wu Zhixiang Dong Xinyi Wang Qing Zhang Heng Wang Dou Wang Jiong Chen 

机构地区：[1]MOE Key Laboratory of Model Animals for Disease Study,Model Animal Research Center,Jiangsu Key Laboratory of Molecular Medicine,Medical School of Nanjing University,Nanjing,Jiangsu 210008,China [2]State Key Laboratory of Molecular Developmental Biology,Institute of Genetics and Developmental Biology,Chinese Academy of Sciences,Beijing 100101,China

出　　处：《Journal of Genetics and Genomics》2023年第1期46-49,共4页遗传学报（英文版）

基　　金：supported by grants from the National Natural Science Foundation of China(31970743);the Fundamental Research Funds for the Central Universities(021414380524)to JC;grants from the National Natural Science Foundation of China(31900563);Natural Science Foundation of Jiangsu Province(BK20190303)to HW。

摘　　要：Collective cell migration plays critical roles in various developmental,physiological,and pathological processes such as morphogenesis,wound healing,and tumor metastasis(Friedl and Gilmour,2009).During collective migration,each coherent group of associated cells needs to interpret external directional signal and convert it into a front-back asymmetry across a collective group(Rorth,2011).But the underlying mechanism for the establishment and maintenance of front-back asymmetry during collective migration is still not well understood.

关 键 词：HEALING COLLECTIVE WOUND 

分 类 号：R73[医药卫生—肿瘤]