竹叶柴胡总黄酮提取及抗氧化作用研究  

Study on Extraction Technology and Antioxidant of Total Flavonoids From Bupleurum Bamboos

作　　者：陈桐 侯林清 覃凡倚 甘鑫睿 叶峻 CHEN Tong;HOU Lin-qing;QIN fan-yi;GAN Xin-rui;YE Jun(College of Chemistry and Life Science,Chengdu Normal University,Chengdu Sichuan 611130,China)

机构地区：[1]成都师范学院化学与生命科学学院,四川成都611130

出　　处：《辽宁化工》2023年第2期187-189,193,共4页Liaoning Chemical Industry

基　　金：四川省大学生创新创业训练项目(项目编号:S202014389158)。

摘　　要：为探究竹叶柴胡的药效机理,采用超声辅助法提取了竹叶柴胡中总黄酮,并确定了最佳工艺如下:提取剂为40%乙醇,料液比为1∶55,超声功率为200 W,温度为70℃,时间为50 min。所测样品中总黄酮质量分数为46.45 g·kg^(-1),且竹叶柴胡提取液对DPPH和羟基自由基均有较好的清除率。研究表明,竹叶柴胡有较好的抗氧化活性,具有抗病毒、抗衰老、抗癌等药效作用。To explore the pharmacodynamic mechanism of Bamboo-leaf Bupleurum,total flavonoids were extracted from Bamboo-leaf Bupleurum by ultrasonic-assisted extraction process,and the optimum process was determined as follows:extraction agent 40%ethanol,solid-liquid ratio 1∶55,ultrasonic power 200 W,extraction temperature 70℃,extraction time 50 min.The total mass fraction of flavonoids in the samples was 46.45 g·kg^(-1).DPPH and HYDROXyl radical scavenging rate of bupleurum bambusifolia extract were good.The results showed that Bupleurum bamboo-leaves had good antioxidant activity and anti-virus,anti-aging and anti-cancer effects.

关 键 词：竹叶柴胡 超声辅助 总黄酮 抗氧化活性 

分 类 号：R284.2[医药卫生—中药学]