关注基于临床需求的肺癌病理诊断新进展  

Advances of pathological diagnosis of lung cancer based on clinical needs

作　　者：曲杨 应建明 Qu Yang;Ying Jianming(Department of Pathology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China)

机构地区：[1]国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院、北京协和医学院、肿瘤医院病理科,北京100021

出　　处：《中华病理学杂志》2023年第2期103-106,共4页Chinese Journal of Pathology

基　　金：国家自然科学基金(82172876);中国医学科学院卫生与健康科技创新工程项目(2021-1-I2M-012);北京市卫生健康委员会首都卫生发展科研专项(首发2022-2-4027)。

摘　　要：为满足肿瘤精准治疗时代的临床需求,肺癌的病理诊断也在不断更新和发展,主要体现在肺癌组织学分类的不断更新、用于指导靶向药物治疗的分子检测、免疫治疗相关标志物的检测及新辅助治疗后病理评估方面的进展。新时代肺癌病理诊断体现了临床-影像-病理等多学科诊断模式,正在逐步走向规范化、精准化,以期更好地为临床提供治疗及预后指导。Pathological diagnosis of lung cancer keep updating and developing,in order to meet the clinical needs in the era of precision medicine.It mainly involves the advances of histological subtype classification,molecular testing for targeted therapy,biomarkers detection for immunotherapy and the pathological evaluation for neoadjuvant therapy.Nowadays,pathological diagnosis of lung cancer present a multidisciplinary model including clinical medicine,radiology and pathology.It is gradually moving towards standardization with expection to provide better guidance for clinical treatment and prognosis.

关 键 词：临床需求 组织学分类 新辅助治疗 病理诊断 精准治疗 治疗及预后 诊断模式 免疫治疗 

分 类 号：R734.2[医药卫生—肿瘤]