纳米材料在肿瘤光动力治疗中的研究进展  

Progress in Nanomaterials for Tumor Photodynamic Therapy

作　　者：张远东 张卓 董紫薇 阚君满 Zhang Yuandong;Zhang Zhuo;Dong Ziwei;Kan Junman(Department of Scientific Research,Jilin Business and Technology College,Changchun,130507;School of Grain Science and Technology,Jilin Business and Technology College,Changchun,130507)

机构地区：[1]吉林工商学院科研处,长春130507 [2]吉林工商学院粮食学院,长春130507

出　　处：《化学通报》2023年第2期173-178,共6页Chemistry

基　　金：吉林省教育厅项目(JJKH20220210KJ);吉林工商学院科研项目(KB2021[003])资助。

摘　　要：光动力治疗是新兴的非侵入性癌症治疗方法。纳米材料以其独特的结构以及光物理、光化学性质成为可用于光动力治疗的光敏剂。根据纳米材料的不同种类,分别对无机非金属纳米材料、无机金属纳米材料、有机小分子纳米材料以及有机聚合物纳米材料等的构建策略及其在光动力治疗肿瘤中的应用进行综述。展望了纳米材料在未来肿瘤光动力治疗中的挑战和发展方向。为新一代纳米光敏剂的构建提供创新思路,并扩展其在癌症治疗中的潜力。Photodynamic therapy has emerged as an innovative non-invasive treatment for cancer.Nanomaterials with distinctive structure,photophysical and photochemical properties have been utilized as photosensitizer for photodynamic therapy of tumors.The construction strategies of nanomaterials and their applications in photodynamic therapy are reviewed according to the different categories of nanomaterials,such as inorganic non-metallic nanomaterials,inorganic metallic nanomaterials,organic small molecule nanomaterials,and organic polymeric nanomaterials.The future challenges and development directions of the nanomaterials in photodynamic therapy are prospected.It is expected that this paper will provide innovative ideas for constructing a new generation of nanophotosensitizers and expand their potential applications in cancer treatment.

关 键 词：肿瘤 光动力治疗 纳米材料 

分 类 号：TB383.1[一般工业技术—材料科学与工程] R730.5[医药卫生—肿瘤]