全腔镜手术与开胸手术在食管癌患者围手术期指标、外周血T细胞亚群和并发症上的差异  

The Difference of Perioperative Indexes, Peripheral Blood T Cell Subsets and Complications between Total Endoscopic Surgery and Thoracotomy in Patients with Esophageal Cancer

作　　者：赵和平 林峰[1] ZHAO Heping;LIN Feng(Macheng People's Hospital,Macheng 438300,China;不详)

机构地区：[1]麻城市人民医院,湖北麻城438300

出　　处：《中外医学研究》2023年第5期103-106,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:对比分析全腔镜手术和开胸手术治疗在食管癌患者围手术期指标、外周血T细胞亚群和并发症上的差异性。方法:选取麻城市人民医院2018年12月—2021年12月收治的食管癌患者150例,按照手术方式的不同将其分为腔镜组(n=79)和开胸组(n=71)。观察两组围手术期指标、T细胞亚群的变化情况及并发症发生率。结果:腔镜组术中出血量明显低于开胸组(P<0.05),手术时间和住院时间均明显短于开胸组(P<0.05)。术后腔镜组CD3^(^(+))、CD4^(+)、CD4^(+)/CD8^(+)均明显高于开胸组(P<0.05),两组CD8^(+)比较,差异无统计学意义(P>0.05)。腔镜组术后并发症的总发生率明显低于开胸组(P<0.05)。结论:与开胸手术相比,食管癌患者应用全腔镜手术能有效降低术中出血量,缩短手术时间和住院时间,对患者外周血T细胞亚群影响相对较小,可减少术后并发症的发生风险。Objective: To compare and analyze the differences of perioperative indexes, peripheral blood T cell subsets and complications between total endoscopic surgery and thoracotomy in patients with esophageal cancer. Method: A total of 150 patients with esophageal cancer admitted to the Macheng People’s Hospital from December 2018 to December 2021, they were divided into endoscopic group(n=79) and thoracotomy group(n=71) according to different surgical methods. The changes of perioperative indexes, T cell subsets and the incidence of complications were observed in the two groups. Result: The intraoperative blood loss in the endoscopic group was significantly lower than that in the thoracotomy group(P<0.05), and the operative time and hospital stay were significantly shorter than those in the thoracotomy group(P<0.05). CD3^(+), CD4^(+), CD4^(+)/CD8^(+) in the endoscopic group were significantly higher than those in the thoracotomy group(P<0.05), and there was no significant difference in CD8^(+) between the two groups(P>0.05). The total incidence of postoperative complications in the endoscopic group was significantly lower than that in the thoracotomy group(P<0.05). Conclusion: Compared with thoracotomy, total endoscopic surgery for patients with esophageal cancer can effectively reduce intraoperative blood loss, shorten operation time and hospital stay, and have relatively little effect on peripheral blood T cell subsets of patients, thus reducing the risk of postoperative complications.

关 键 词：食管癌 全腔镜手术 开胸手术 T细胞亚群 

分 类 号：R735.1[医药卫生—肿瘤]