幽門螺桿菌感染與胃黏膜病理變化的關係  

The relationship between Helicobacter pylori infections and pathological change of gastric mucosa

作　　者：肖剛 陳建勇 冼麗芳 韋潔貞 葉玉清 古杰鳴 文劍明 XIAO Gang;CHAN Kin Iong;SIN Lai Fong;WAI Kit Cheng;YIP Yuk Ching;KU Kit Ming;Wen Jian Ming(Department of Pathology,Kiang Wu Hospital,Macao,China)

机构地区：[1]澳門鏡湖醫院病理科,中國

出　　处：《镜湖医学》2015年第1期14-15,共2页MEDICAL JOURNAL OF KIANG WU

摘　　要：目的研究幽門螺桿菌(H.pylori)感染與胃黏膜病變的關係。方法選取有上消化道癥狀的患者1073例,分別進行胃鏡、病理組織學及H.pylori檢測。結果全部1073例患者中有353例H.pylori陽性,陽性率為32.9%。H.pylori感染者胃黏膜活動性炎症、淋巴濾泡形成顯著高於H.pylori陰性者(P<0.05),而H.pylori感染與腸上皮化生、萎縮無顯著性差異。結論胃黏膜病變與H.pylori感染密切相關,胃黏膜活檢對H.pylori感染有診斷價值。Objective To analysis the relationship between Helicobacter pylori(H.pylori)infection and pathological change of gastric mucosa.Methods 1073 patients with upper digestive symptom were investigated in this study.All patients underwent examinations including upper digestive endoscopy,pathologic histology and H.pylori infection test.Results 353 cases were H.pylori positive in 1073 patients and the positive rate was 32.9%.In chronic gastritis patients,the active inflammation and lymph follicle formation rate in H.pylori infection patients were significantly higher than that in H.pylori negative patients(P<0.05),but there was no significant difference on intestinal metaplasia and atrophy.Conclusion The gastric mucosa lesions were closely correlated with H.pylori infection.Gastric mucosa biopsy pathology is valuable in diagnosis of H.pylori infection.

关 键 词：胃炎 幽門螺桿菌 病理變化 

分 类 号：R57[医药卫生—消化系统]