微生物检验在尿路感染预防和诊疗中的应用  

Application of microbiological examination in prevention, diagnosis and treatment of urinary tract infection

作　　者：王艳侠[1] Wang Yanxia(Department of Clinical Laboratory,Jinxiang County People's Hospital,Jining 272200,Shandong,China)

机构地区：[1]金乡县人民医院检验科,山东济宁272200

出　　处：《实用检验医师杂志》2022年第4期373-376,共4页Chinese Journal of Clinical Pathologist

摘　　要：目的 探讨微生物检验在尿路感染的预防、诊断和治疗中的应用价值。方法 选择2019年7月—2020年7月金乡县人民医院收治的130例尿路感染患者作为研究对象,其中65例纳入常规检验组,进行常规检验并根据经验开展用药治疗;另外65例纳入微生物检验组,进行微生物检验,并根据检验结果开展针对性抗菌药物治疗。分析两组患者的一般资料及诊断结果,统计治疗效果、治疗后感染情况、病原菌种类以及药敏试验结果。结果 微生物检验组的诊断准确率和治疗总有效率均明显高于常规检验组[诊断准确率:96.92%(63/65)比84.62%(55/65),治疗总有效率:93.85%(61/65)比76.92%(50/65),均P<0.05]。微生物检验组治疗后只有2例患者(3.08%)出现轻度感染,未出现中度和重度感染患者。微生物检验组的重度感染率和总感染率均明显低于常规检验组[重度感染率:0.00%(0/65)比9.23%(6/65),总感染率:3.08%(2/65)比21.54%(14/65),均P<0.05]。微生物检验组患者感染的致病菌中检出大肠埃希菌最多(43例),检出率为66.15%。药敏试验结果显示,致病菌对抗菌药物阿米卡星、亚胺培南的敏感率均较高,分别为95.52%、100.00%。结论 在尿路感染患者的预防与诊疗中,应用微生物检验的效果较好,能够得到较高的诊断准确率与治疗有效率,重度感染率较低。Objective To explore the application value of microbiological examination in the prevention,diagnosis and treatment of urinary tract infection. Methods The 130 patients with urinary tract infection admitted in Jinxiang County People’s Hospital from July 2019 to July 2020 were selected as research objects. The 65 cases were included in the conventional test group, and conventional test was performed and drug treatment was carried out according to experience;other 65 cases were included in the microbiological test group for microbiological test,and targeted antimicrobial treatment was carried out according to the test results. The general data and diagnosis results of the two groups of patients were analyzed, and the treatment effect, infection after treatment, pathogen types and drug sensitivity test results were investigated. Results The diagnostic accuracy and total effective rate of treatment in the microbiological test group were higher than those in the conventional test group [diagnostic accuracy: 96.92%(63/65) vs. 84.62%(55/65), total effective rate of treatment: 93.85%(61/65) vs. 76.92%(50/65),both P < 0.05]. After treatment, only two patients(3.08%) in the microbiological test group had mild infection, but no moderate or severe infection. The severe infection rate and total infection rate in the microbiological test group after treatment were lower than those in the conventional test group [severe infection rate: 0.00%(0/65) vs. 9.23%(6/65), total infection rate: 3.08%(2/65) vs. 21.54%(14/65), both P < 0.05]. In the microbiological test group, the most pathogenic bacteria were Escherichia coli(43 cases), with a detectable rate of 66.15%. The results of drug sensitivity test showed that the sensitivity of pathogenic bacteria to the antibacterial drugs Amikacin and Imipenem were 95.52% and 100.00%. Conclusion In the prevention, diagnosis and treatment of patients with urinary tract infection, the application of microbiological test has a good effect, which could obtain a higher diagnostic accuracy and tre

关 键 词：微生物检验 尿路感染 诊断结果 治疗效果 重度感染 

分 类 号：R446.5[医药卫生—诊断学] R691.3[医药卫生—临床医学]