机构地区:[1]蚌埠医学院研究生院,233030 [2]中国科学技术大学附属第一医院 [3]安徽医科大学研究生院
出 处:《临床眼科杂志》2023年第1期19-22,共4页Journal of Clinical Ophthalmology
基 金:国家自然科学基金项目(No.82070977);中国科学技术大学附属第一医院(安徽省立医院)院助项目(No.2019zc047)。
摘 要:目的对比观察改良式23G免缝合切口硅油取出手术的临床疗效及安全性。方法前瞻性随机对照研究。将28例(28只眼)随机分成两组,改良式23G免缝合切口硅油取出手术组为实验组(n=11),传统23G缝合切口硅油取出手术组为对照组(n=17),术前患者视网膜均完全复位。对比观察两组手术时间、术前,术后1 d、2个月眼压、角膜散光、最佳矫正视力、术后1 d结膜充血水肿程度,术后相关并发症发生情况,并通过眼表疾病指数(OSDI)量表调查评估患眼术后1周反应情况。结果两组在手术时间上差异无统计学意义(P>0.05)。术后1 d、2个月眼压、最佳矫正视力均无统计学意义(P>0.05);术后1 d角膜散光,实验组平均值远低于对照组,差异有统计学意义(P<0.05),术后2个月实验组的角膜散光平均值虽仍低于对照组,但无统计学意义(P>0.05);术后1 d,对照组结膜充血水肿程度较实验组明显。术后1周,眼表疾病指数(OSDI)量表调查结果有统计学意义(P>0.05);随访期间,实验组和对照组术后1 d各有1例(1只眼)患者发生一过性低眼压、对照组有1例(1只眼)视网膜再脱离,两组术后均未有眼内炎的发生。结论改良式23G免缝合切口硅油取出术可以安全有效地取出硅油,同时降低术后早期角膜散光,减轻结膜充血水肿程度,对于减轻患者术后的眼部不适,提高患眼术后舒适度具有明显优势。Objective To compare and analyse the clinical efficacy and safety of silicone oil removal with modified 23-gauge(G)sutureless incision vitrectomy system.Methods A prospective case-control study.28 patients were randomly divided into two groups.Patients receiving silicone oil removal with modified 23G sutureless incision vitrectomy system were assigned to the test group(n=11),and patients receiving silicone oil removal with conventional 23G sutured vitrectomy system were assigned to the control group(n=17).The retina was completely reattached before the operation.Statistical analyses were performed in terms of operative time,intraocular pressure(IOP),corneal astigmatism,best-corrected visual acuity(BCVA),the degree of conjunctival congestion and oedema,and postoperative complications between the two groups,and adverse responses of the affected eyes at 1 week after surgery were evaluated by the Ocular Surface Disease Index(OSDI)scale.Results There was no statistically significant difference in the operative time between the two groups(P>0.05).The IOP and BCVA at 1 day and 2 months after surgery were not statistically significant(P>0.05).The mean value of corneal astigmatism in the experimental group at 1 day after surgery was much lower than that in the control group(P<0.05).The mean value of corneal astigmatism in 2 months group was still lower than that in the control group,but there was no statistical significance(P>0.05).The degree of conjunctival congestion and edema in the control group at postoperative 1 day was significantly higher than that in the experimental group.At 1 week after surgery,the results of the OSDI scale were statistically significant(P>0.05).During the follow-up period,one case of transient hypotony occurred in each of the experimental groups and one case of retinal re-detachment in the control group,and no endophthalmitis occurred in both groups after surgery.conclusions Silicone oil removal with modified 23G sutureless incision vitrectomy system is safe and effective.It also reduces corne
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