Glycogen overload transforms the liver  

作　　者：Peiyi Li Tingting Qiu Bolong Liu Jianxin Zhang Yehua Dai Hong Zhao 

机构地区：[1]Nursing College,Hengyang Medical School,University of South China,Hengyang 421001,China [2]The Central Hospital of Changsha City,Hengyang Medical School,University of South China,Changsha 410000,China [3]The First Affiliated Hospital,University of South China,Hengyang Medical School,University of South China,Hengyang 421001,China [4]Affiliated Nanhua Hospital,University of South China,Hengyang Medical School,University of South China,Hengyang 421001,China [5]Nursing College,University of Xiangnan,Chenzhou 423000,China

出　　处：《Acta Biochimica et Biophysica Sinica》2022年第12期1939-1941,共3页生物化学与生物物理学报（英文版）

基　　金：supported by the grants from the Hunan Province Natural Science Foundation(Nos.2021JJ30606,2022JJ70120,and 2022JJ70039);the General Project of Hunan Provincial Health Commission(No.202102060874).

摘　　要：Glycogen,a fast and accessible form of energy,can provide organisms with glucose on demand.It is mainly present in the liver and skeletal muscles,with small amounts in the brain,heart,kidney,adipose tissue,and red blood cells[1].Numerous enzymes are involved in glycogen synthesis,including glycogen synthase(GS),glycogen branching enzyme,and protein phosphatase 1.Many enzymes are linked to glycogen degradation,including glycogen phosphorylase(GP),glycogen debranching enzyme,and glucose-6-phosphatase(G6PC).Defective glycogen metabolism-related enzymes result in glycogen accumulation.

关 键 词：branching METABOLISM accumulation. 

分 类 号：R575[医药卫生—消化系统]