早期声门型喉癌患者放疗的临床疗效观察与预后影响因素分析  

Observation of Clinical Effect and Prognostic Factors of Radiotherapy in Patients with Early Glottal Laryngeal Carcinoma

作　　者：刘沛[1] 翟红丽[1] 程呈 LIU Pei;ZHAI Hongli;CHENG Cheng(The First Affiliated Hospital of Zhengzhou University,Zhengzhou,450000)

机构地区：[1]郑州大学第一附属医院,450000

出　　处：《实用癌症杂志》2023年第3期437-439,共3页The Practical Journal of Cancer

摘　　要：目的 分析早期声门型喉癌患者放疗的临床疗效与预后影响因素。方法 选取早期声门型喉癌患者102例,均行常规放疗,统计疗效、复发率,采用自制调查问卷收集患者性别、年龄、分化程度、临床分期、淋巴结转移信息,分析预后影响因素。结果 放疗总有效率为88.24%(90/102),复发率为17.65%(18/102)。性别、年龄、临床分期、淋巴结转移是影响声门型喉癌患者预后的单因素(P<0.05);logistic回归分析显示,男性、≥60岁、Ⅱ期、存在淋巴结转移是声门型喉癌预后的危险因素(P<0.05)。结论 早期声门型喉癌患者应用放疗治疗效果确切,但仍存在复发风险,且老年、男性、临床分期Ⅱ期、淋巴结转移是声门型喉癌患者预后危险因素,临床可据此实施防控措施。Objective To analyze the clinical efficacy and prognostic factors of radiotherapy in patients with early glottal laryngeal cancer.Methods 102 patients with early glottic laryngeal cancer were treated with conventional radiotherapy, statistical efficacy and recurrence rate, age, differentiation, clinical stage, lymph node metastasis, and analyzed prognostic factors.Results The total response rate of radiotherapy was 88.24%(90/102),and the recurrence rate was 17.65%(18/102).Sex, age, clinical stage, and lymph node metastasis were univariates(P<0.05) in patients with 160 laryngeal cancer;logistic regression analysis showed that men, ≥60,stage Ⅱ,and lymph node metastasis were risk factors for glottal laryngeal carcinoma(P<0.05).Conclusion Radiotherapy for early glottic laryngeal cancer is effective, with risk of recurrence, and edlerly, men, stage Ⅱ,and lymph node metastasis are risk factors for prognosis of glottal laryngeal carcinoma, Measures should be taken in clinic.

关 键 词：早期声门型喉癌 放疗 临床疗效 预后影响因素 

分 类 号：R739.65[医药卫生—肿瘤]