Human symbiont Bacteroides xylanisolvens attenuates NASH through intestinal nicotine catabolism  

作　　者：HU Haiming LAN Ke LIU Hongtao 

机构地区：[1]College of Basic Medical Sciences,Hubei University of Chinese Medicine,Wuhan 430065,China

出　　处：《Chinese Journal of Natural Medicines》2023年第2期81-82,共2页中国天然药物（英文版）

基　　金：supported by the Major Science and Technology Project in Yunnan Province(No.202102AE090042);the Health Commission of Hubei Province of China(No.ZY2021M107 and ZY2019Q003);the Educational Commission of Hubei Province of China(No.D20212003).

摘　　要：Tobacco use increases the risk of many diseases,such as lung cancer,chronic obstructive pulmonary disease,and coronary heart disease.Smoking is the most preventable cause of death,responsible for over 6 million deaths worldwide each year.The average life expectancy of smokers is reduced by 10 years compared to those who never smoke^([1]).Nicotine accumulates in the upper gastrointestinal tract during smoking,which may lead to pathological damage.Smoking is positively associated with the development of nonalcoholic fatty liver disease(NAFLD).

关 键 词：Non-alcoholic fatty liver disease Gut microbiota NICOTINE Drug metabolism 

分 类 号：R965[医药卫生—药理学]