母细胞性浆细胞样树突状细胞肿瘤伴急性髓系白血病一例  

Blastic plasmacytoid dendritic cell neoplasm complicated with acute myeloid leukemia:a case report

作　　者：孔利华 秦丽莉[2] 冯安华[2] 刘真真 唐娜 臧继康 王海英[2] Kong Lihua;Qin Lili;Feng Anhua;Liu Zhenzhen;Tang Na;Zang Jikang;Wang Haiying(Affiliated Hospital of Weifang Medical University,School of Clinical Medicine,Weifang 261000,China)

机构地区：[1]潍坊医学院附属医院(临床医学院),潍坊261000 [2]潍坊医学院附属医院血液科,潍坊261000

出　　处：《新医学》2023年第3期216-220,共5页Journal of New Medicine

摘　　要：母细胞性浆细胞样树突状细胞肿瘤(BPDCN)伴急性髓系白血病(AML)罕见,该文报道了1例以发热为首发症状的BPDCN伴AML患者的诊治过程以提高临床医师的诊治水平。该例患者为69岁男性,因发热1周入院,无典型的皮肤损害表现,骨髓涂片细胞形态学分析示增生极度活跃,且瘤细胞免疫表型独特,确诊为BPDCN伴AML。建议其选择含维奈克拉的低强度化学治疗方案,但患者放弃治疗。Blastic plasmacytoid dendritic cell neoplasm(BPDCN)complicated with acute myeloid leukemia(AML)is a rare disease.In this article,we reported the diagnosis and treatment of one patient of BPDCN complicated with AML who presented with fever as the first symptom,aiming to enhance the diagnostic and therapeutic capability of clinicians for this disease.The male patient,aged 69 years old,was admitted to hospital due to fever for 1 week.He had no typical skin lesions.Morphological and cytological observation of bone marrow smear showed extremely active hyperplasia and tumor cells with specific immunophenotype.The diagnosis of BPDCN complicated with AML was confirmed.A low-intensity venetoclax-based chemotherapy regimen was recommended.However,the patient discontinued further treatment.

关 键 词：母细胞性浆细胞样树突状细胞肿瘤 急性髓系白血病 诊断 治疗 

分 类 号：R733.71[医药卫生—肿瘤]