2012—2021年宁波市脑卒中发病和死亡趋势分析  

Trends in incidence and mortality of stroke in Ningbo City from 2012 to 2021

作　　者：张瑞洁 纪威[3] 韩丽媛 张良[3] ZHANG Ruijie;JI Wei;HAN Liyuan;ZHANG Liang(Zhejiang Provincial Key Laboratory of Diagnosis and Treatment of Digestive System Tumors,Ningbo NO.2 Hospital,Ningbo,Zhejiang 315010,China;Center for Cardiovascular and Cerebrovascular Epidemiology and Translational Medicine,Ningbo Institute of Life and Health Industry,University of Chinese Academy of Sciences,Ningbo,Zhejiang 315010,China;Ningbo Center for Disease Control and Prevention,Ningbo,Zhejiang 315010,China)

机构地区：[1]宁波市第二医院浙江省消化系统肿瘤诊治和研究重点实验室,浙江宁波315010 [2]国科宁波生命与健康产业研究院心脑血管流行病学与转化医学中心,浙江宁波315010 [3]宁波市疾病预防控制中心,浙江宁波315010

出　　处：《预防医学》2023年第3期224-228,共5页CHINA PREVENTIVE MEDICINE JOURNAL

基　　金：科技创新2025重大专项(2018B10073);浙江省医药卫生科技计划(2022488610);中国科学院大学宁波华美医院华美研究基金一般项目(2021HMKY17)。

摘　　要：目的了解2012—2021年浙江省宁波市居民脑卒中发病和死亡趋势,为完善宁波市脑卒中防控策略提供依据。方法通过宁波市慢性病协同管理系统收集2012—2021年宁波市脑卒中发病和死亡资料,计算发病率和死亡率,采用2010年第六次全国人口普查数据进行标化。采用年度变化百分比(APC)分析发病率和死亡率的变化趋势。结果2012—2021年宁波市居民脑卒中发病185747例,粗发病率为312.78/10万,呈上升趋势,APC值为2.429%(t=5.507,P=0.001);标化发病率为188.86/10万,未见明显变化趋势,APC值为-0.399%(t=-1.544,P=0.161)。脑卒中死亡47355例,粗死亡率和标化死亡率分别为79.74/10万和42.79/10万,均呈下降趋势,APC值分别为-4.778%(t=-6.867,P<0.001)和-8.269%(t=-13.729,P<0.001)。男性脑卒中标化发病率和标化死亡率分别为226.05/10万和50.14/10万,均高于女性的153.37/10万和35.89/10万。脑卒中粗发病率和粗死亡率均随年龄增长呈上升趋势(χ^(2)_(趋势)=3671.325、1419.107,均P<0.001)。出血性脑卒中标化发病率和标化死亡率分别为40.38/10万和18.56/10万,均呈下降趋势,APC值分别为-5.042%(t=-12.958,P<0.001)和-11.570%(t=-14.979,P<0.001)。缺血性脑卒中标化发病率为143.91/10万,呈上升趋势,APC值为1.254%(t=3.223,P=0.012);标化死亡率为19.65/10万,未见明显变化趋势,APC值为-2.110%(t=-2.150,P=0.064)。结论2012—2021年宁波市居民脑卒中发病率呈上升趋势,死亡率呈下降趋势。男性和老年人是脑卒中防治的高危人群。Objective To investigate the trends in incidence and mortality of stroke in Ningbo City,Zhejiang Province from 2012 to 2021,so as to provide the evidence for improving the stroke control strategy in Ningbo City.Methods Data pertaining to the stroke incidence and mortality in Ningbo City from 2012 to 2021 were captured from Ningbo Mu-nicipal Chronic Disease Collaborative Management System,and the incidence and mortality of stroke was estimated and standardized by the Sixth National Population Census in 2010.The trends in incidence and mortality of stroke were evaluated using annual percent change(APC)in Ningbo City from 2012 to 2021.ResultsA total of 185747 resi-dents with stroke were reported in Ningbo City from 2012 to 2021.The crude incidence of stroke was 312.78/10^(5)in Ningbo City from 2012 to 2021,which appeared a tendency towards a rise(APC=2.429%,t=5.507,P<0.001),and the standardized incidence of stroke was 188.86/10^(5),with no remarkable changes seen(APC=-0.399%,t=-1.544,P=0.161).There were 47355 deaths due to stroke in Ningbo City from 2012 to 2021,and the crude and standardized mortality rates were 79.74/10^(5)and 42.79/10^(5),which both appeared a tendency towards a decline(APC=-4.778%,t=-6.867,P<0.001;APC=-8.269%,t=-13.729,P<0.001).Higher standardized incidence and mortality were seen among men(226.05/10^(5)and 50.14/10^(5))than among women(153.37/10^(5)and 35.89/10^(5)),and the crude incidence and mortality of stroke appeared a tendency towards a rise with age(χ^(2)_(trend)=3671.325,1419.107,both P<0.001).The standardized inci-dence and mortality of hemorrhagic stroke were 40.38/10^(5)and 18.56/10^(5),both showing a tendency towards a decline(APC=-5.042%,t=-12.958,P<0.001;APC=-11.570%,t=-14.979,P<0.001),and the standardized incidence of isch-emic stroke was 143.91/10^(5),appearing a tendency towards a rise(APC=1.254%,t=3.223,P=0.012),while the standard-ized mortality of ischemic stroke was 19.65/10^(5),with no obvious changes seen(APC=-2.110%,t=-2.150,P=0.064).ConclusionsThe incidence of stroke ap

关 键 词：脑卒中 发病率 死亡率 宁波市 

分 类 号：R743.3[医药卫生—神经病学与精神病学]