2011~2018年沈阳市城区居民肺癌发病及死亡趋势分析  

Trend in New Cases and Deaths of Lung Cancer among Urban Residents in Shenyang from 2011 to 2018

作　　者：吕艺[1] 张馨予 聂慧芳 赵雪 李恂[1] LüYi;Zhang Xinyu;Nie Huifang;Zhao Xue;Li Xun(Institute for Chronic Disease Control and Prevention,Shenyang Center for Disease Control and Prevention,Shenyang 110068,Liaoning,China;Department of Foreign Language,Information Engineering University,Luoyang 471003,Henan,China)

机构地区：[1]沈阳市疾病预防控制中心慢性病防制所,沈阳110068 [2]信息工程大学外国语学院,河南洛阳471003

出　　处：《肿瘤预防与治疗》2023年第2期117-124,共8页Journal of Cancer Control And Treatment

基　　金：辽宁省自然科学基金指导计划项目(编号:20180550495)。

摘　　要：目的:了解2011~2018年沈阳市肿瘤登记地区肺癌的发病和死亡趋势,为开展肺癌防治提供建议。方法:收集2011~2018年沈阳市肿瘤登记地区肺癌的发病死亡病例。计算肺癌的发病率、死亡率、标化率、截缩率(35~64岁)、累积率(0~74岁)和发病、死亡顺位等指标;采用Joinpoint 3.5.3软件计算发病率、死亡率、截缩率和累积率的年度变化百分比(annual percentage change,APC);采用SPSS 23.0统计软件对肺癌男女发病率及死亡率进行χ^(2)检验。结果:2011~2018年沈阳市城区肺癌粗发病率为86.99/10万,中标率40.51/10万,世标率40.65/10万,累积率(0~74岁)为4.91%,截缩率(35~64岁)为56.50/10万;男性发病顺位肺癌为第1位,女性为第2位,发病率男性高于女性(χ^(2)=1682.65,P<0.01)。2011~2018年沈阳市城区肺癌粗死亡率为66.08/10万,中标率29.83/10万,世标率29.64/10万,累积率为(0~74岁)3.41%,截缩率(35~64岁)为34.82/10万;男女死亡顺位肺癌均为第1位,死亡率男性高于女性(χ^(2)=1475.27,P<0.01)。8年间沈阳市男性肺癌发病和男女死亡标化率均呈先上升(P<0.05)后下降(P>0.05),女性发病持续上升趋势(P<0.05);结论:沈阳市肺癌发病率和死亡率在全国处于较高水平,且女性发病率持续上升,应重点加强高危人群的健康教育,建立肺癌早期筛查机制。Objectives:To investigate the trend in incidence and mortality of lung cancer in tumor registration areas of Shenyang from 2011 to 2018,and provide suggestions for the prevention and treatment of lung cancer.Methods:New cases and deaths of lung cancer in tumor registration areas of Shenyang from 2011 to 2018 were collected.The incidence rate,mortality rate,age-standardized rate,truncated rate(35-64 years old),cumulative rate(0-74 years old)and incidence and mortality ranks of lung cancer were calculated.Joinpoint 3.5.3 was used to calculate the annual percentage changes of incidence rate,mortality rate,truncated rate and cumulative rate.Chisquare test was performed with SPSS 23.0 for the incidence and mortality rates of lung cancer in males and females.Results:From 2011 to 2018,the crude incidence of lung cancer in Shenyang was 86.99/10 million,and the age-standardized incidence rates by Chinese standard population and world standard population were 40.51/10 million and 40.65/10 million,respectively;the cumulative rate(0-74 years old)was 4.91%,and the truncated rate(35-64 years old)was 56.50/10 million;lung cancer ranked first in males,and second in females;the incidence rate was higher in males than in females(χ^(2)=1,682.65,P<0.01).During the same period,the crude mortality rate of lung cancer in Shenyang was 66.08/10 million,and the age-standardized mortality rates by Chinese standard population and world standard population were 29.83/10 million and 29.64/10 million,respectively;the cumulative rate(0-74 years old)was 3.41%,and the truncated rate(35-64 years old)was 34.82/10 million;lung cancer ranked first in both sexes,and the mortality rate was higher in males than in females(χ^(2)=1,475.27,P<0.01).The incidence rate of lung cancer in males in Shenyang and age-standardized mortality rates in both sexes increased(P<0.05)before decreased(P>0.05)from 2011 to 2018,and the incidence in females continued to rise(P<0.05).Conclusion:The incidence and mortality rates of lung cancer in Shenyang were at a high level

关 键 词：肺癌 发病率 死亡率 截缩率 累积率 变化趋势 

分 类 号：R734.2[医药卫生—肿瘤]