血清Hcy、hs-CRP、D-D水平检测在急性脑梗死诊断中的临床价值  

Clinical Value of Serum Hcy, hs-CRP and D-D levels in the Diagnosis of Acute Cerebral Infarction

作　　者：何俊鹏 HE Junpeng(the First Hospital of Dandong City,Dandong 118000,China)

机构地区：[1]辽宁省丹东市第一医院,辽宁丹东118000

出　　处：《中国医药指南》2023年第5期130-132,共3页Guide of China Medicine

摘　　要：目的 探讨血清同型半胱氨酸(Hcy)、超敏C反应蛋白(hs-CRP)、D-二聚体(D-D)水平检测在急性脑梗死诊断中的临床价值。方法 选择我院2018年1月至2019年6月收治的60例急性脑梗死患者作为本次研究入组对象,另选取2018年1月至2019年6月在我院进行体检的结果显示健康的60名健康志愿者作为对照组。比较两组血清Hcy、hs-CRP、D-D水平以及不同梗死面积的急性脑梗死患者血清Hcy、hs-CRP、D-D水平差异。结果 急性脑梗死组和健康对照组血清Hcy、hs-CRP、D-D水平对比,研究组患者经血清检测Hcy、hs-CRP、D-D均高于对照组,组间差异有统计学意义(P<0.05)。急性脑梗死不同梗死面积血清Hcy、hs-CRP、D-D水平对比,大面积梗死患者的血清Hcy、hs-CRP、D-D均高于中、小梗死患者,组间差异有统计学意义(P<0.05)。急性脑梗死不同梗死程度血清Hcy、hs-CRP、D-D水平对比,重度梗死患者的血清Hcy、hs-CRP、D-D均高于轻、中度梗死患者,组间差异有统计学意义(P<0.05)。结论 血清Hcy、hs-CRP、D-D水平检测在急性脑梗死诊断中的临床应用价值高,不同大小的梗死面积和不同程度的梗死对患者影响不同,临床预后大不相同,经血清Hcy、hs-CRP、D-D水平检测可实现对梗死面积及程度的判断,为临床诊治和预后判断提供重要参考。Objective To investigate the clinical value of serum Hcy, hs-CRP and D-D levels in the diagnosis of acute cerebral infarction.Methods A total of 60 patients with acute cerebral infarction admitted to our hospital from January 2018 to June 2019 were selected as the subjects of this study, and another 60 healthy volunteers who underwent physical examination in our hospital from January 2018 to June 2019 were selected as the control group. The serum levels of Hcy, hs-CRP and D-D were compared between the two groups, and the serum levels of Hcy, hs-CRP and D-D in patients with acute cerebral infarction with different infarct sizes were compared. Results In the comparison of serum levels of Hcy, hs-CRP and D-D between the acute cerebral infarction group and the healthy control group, the serum levels of Hcy, hs-CRP and D-D in the study group were higher than those in the control group, the difference between the groups was statistically significant(P<0.05). In the comparison of serum Hcy,hs-CRP and D-D levels in patients with acute cerebral infarction of different infarction areas, the serum Hcy, hs-CRP and D-D levels in patients with large infarction were higher than those in patients with medium and small infarction, and the difference between groups was statistically significant(P<0.05). The serum levels of Hcy, hs-CRP and D-D in patients with severe infarction were higher than those in patients with mild and moderate infarction, and the difference between groups was statistically significant(P<0.05). Conclusion Serum Hcy, hs-CRP and D-D levels have high clinical application value in the diagnosis of acute cerebral infarction. Different sizes of infarction and different degrees of infarction have different effects on patients, and the clinical prognosis is very different. Serum Hcy, hs-CRP and D-D levels can be used to determine the size and degree of infarction. It provides important reference for clinical diagnosis, treatment and prognosis.

关 键 词：急性脑梗死 血清同型半胱氨酸 超敏C反应蛋白 D-二聚体 诊断价值 

分 类 号：R743[医药卫生—神经病学与精神病学]