中西医结合治疗风痰瘀阻型脑梗死的效果研究  

Clinical study on integrated traditional Chinese and western medicine in the treatment of wind phlegm and blood stasis type of cerebral infarction

作　　者：苗雨丽 MIAO Yu-li(Liaoning Fengtian Hospital of Traditional Chinese Medicine,Shenyang 110000,China)

机构地区：[1]辽宁奉天中医院,110000

出　　处：《中国现代药物应用》2023年第4期148-150,共3页Chinese Journal of Modern Drug Application

摘　　要：目的探讨中西医结合治疗风痰瘀阻型脑梗死的临床效果。方法40例风痰瘀阻型脑梗死患者,随机分为试验组和对照组,各20例。对照组患者采用西医单独治疗,试验组患者在对照组基础上联合化痰通络汤进行治疗。对比两组患者临床疗效、美国国立卫生研究院卒中量表(NIHSS)评分、日常生活活动能力量表(ADL)评分及血清炎症因子(白细胞介素-4、超敏C反应蛋白及肿瘤坏死因子-α)。结果试验组总有效率95.00%显著高于对照组的60.00%,差异有统计学意义(P<0.05)。治疗后,试验组NIHSS评分(9.01±0.98)分显著低于对照组的(12.01±1.67)分,ADL评分(86.01±4.95)分显著高于对照组的(73.21±4.68)分,差异有统计学意义(P<0.05)。治疗后,试验组白细胞介素-4(12.01±1.78)pg/ml、超敏C反应蛋白(7.98±0.53)mg/L及肿瘤坏死因子-α(0.98±0.15)ng/ml均低于对照组的(21.35±2.05)pg/ml、(9.56±0.84)mg/L、(1.28±0.08)ng/ml,差异有统计学意义(P<0.05)。结论风痰瘀阻型脑梗死患者采用中西医结合治疗的临床效果更显著,可明显缓解神经功能缺损,提高生活质量,炎症反应降低更明显,临床上应重视并推广。Objective To discuss the clinical effect of integrated traditional Chinese and Western medicine in the treatment of wind phlegm and blood stasis type of cerebral infarction.Methods A total of 40 patients with wind phlegm and blood stasis type of cerebral infarction were randomly divided into an experimental group and a control group,with 20 patients in each group.Patients in the control group were treated with Western medicine alone,while patients in the experimental group were treated with Huatan Tongluo Decoction on the basis of the control group.Both groups were compared in terms of clinical efficacy,National Institutes of Health Stroke Scale(NIHSS)score,activities of daily living(ADL)score and serum inflammatory factors(interleukin-4,high-sensitivity C-reactive protein and tumor necrosis factor-α).Results The total effective rate of the experimental group was 95.00%,which was significantly higher than 60.00%of the control group,and the difference was statistically significant(P<0.05).After treatment,the NIHSS score(9.01±0.98)points of the experimental group was significantly lower than(12.01±1.67)points of the control group,and the ADL score(86.01±4.95)points of the experimental group was significantly higher than(73.21±4.68)points of the control group.The differences were statistically significant(P<0.05).After treatment,the interleukin-4(12.01±1.78)pg/ml,high-sensitivity C-reactive protein(7.98±0.53)mg/L and tumor necrosis factor-α(0.98±0.15)ng/ml in experimental groups were lower than(21.35±2.05)pg/ml,(9.56±0.84)mg/L and(1.28±0.08)ng/ml in control group,and the differences were statistically significant(P<0.05).Conclusion The clinical effect of integrated traditional Chinese and Western medicine in patients with wind phlegm and blood stasis type of cerebral infarction is more significant,which can obviously relieve the neurological deficit,improve the quality of life,and reduce the inflammatory reactions.It should be paid attention to and popularized in clinic.

关 键 词：风痰瘀阻型脑梗死 化痰通络汤 阿司匹林 硫酸氢氯吡格雷片 阿托伐他汀钙片 

分 类 号：R743.33[医药卫生—神经病学与精神病学]