镇痉化痰汤化裁方联合丙戊酸钠治疗小儿颅脑损伤后继发性癫痫临床观察  

作　　者：徐会民 王品 

机构地区：[1]河南省南阳市中心医院,河南南阳473000

出　　处：《实用中医药杂志》2023年第2期277-279,共3页Journal of Practical Traditional Chinese Medicine

摘　　要：目的:观察镇痉化痰汤化裁方联合丙戊酸钠治疗小儿颅脑损伤后继发性癫痫的效果。方法:56例按照随机数字表法分为对照组和观察组各28例。两组均给予丙戊酸钠片口服,观察组加用镇痉化痰汤化裁方口服。结果:观察组总有效率高于对照组(P<0.05)。治疗4周、治疗8周、治疗12周后,观察组NIHSS评分均低于对照组(P<0.05)。观察组较对照组PIQ、VIQ、FIQ评分高(P<0.05),血清中Hcy、NSE等含量低(P<0.05)。结论:镇痉化痰汤化裁方联合丙戊酸钠对颅脑损伤后继发性癫痫有良好效果。Objective:To observe the effect of Zhenjing Huatan Decoction combined with Sodium Valproate in the treatment of secondary epilepsy after craniocerebral injury in children. Methods: Fifty-six cases were divided into the control group and the observation group according to the random number table method, 28 cases in each group. Both groups were given Sodium Valproate Tablets orally, and the observation group were additionally given Zhenjing Huatan Decoction orally in addition. Results: The total effective rate of the observation group was higher than that of the control group(P<0.05). After 4 weeks, 8 weeks and 12 weeks of treatment, the NIHSS scores of the observation group were lower than those of the control group(P<0.05). The scores of PIQ, VIQ and FIQ in the observation group were higher than those in the control group(P<0.05),and the contents of Hcy and NSE in the serum were lower(P<0.05). Conclusion: Zhenjing Huatan Decoction combined with Sodium Valproate has a good effect on secondary epilepsy after craniocerebral injury.

关 键 词：颅脑损伤后 小儿 继发性癫痫 镇痉化痰汤化裁方 丙戊酸钠 

分 类 号：R742.1[医药卫生—神经病学与精神病学]