自体血胸腔注射在肺切除术后并发气胸中临床应用研究  

Clinical application of autologous blood injection into thoracic cavity in patients with pneumothorax after pulmonary resection

作　　者：岳庆峰[1] 汪永和[1] 魏祥志 张科[1] 江陈[1] 朱军辉 王捷 YUE Qingfeng;WANG Yonghe;WEI Xiangzhi;ZHANG Ke;JIANG Chen;ZHU Junhui;WANG Jie(Department of Thoracic Surgery,The Third People´s Hospital of Hefei(Hefei Third Clinical College of Anhui Medical University),Hefei,Anhui 230022,China)

机构地区：[1]合肥市第三人民医院(安徽医科大学合肥第三临床学院)胸外科,安徽合肥230022

出　　处：《安徽医药》2023年第4期759-762,共4页Anhui Medical and Pharmaceutical Journal

基　　金：合肥市第三人民医院院内基金(hfsyjj202103)。

摘　　要：目的比较自体血胸腔注射和香菇多糖胸腔注射促进胸膜粘连对肺部术后气胸的临床疗效及不良反应。方法选取合肥市第三人民医院(安徽医科大学合肥第三临床学院)2019年1月至2022年8月共46例肺部术后气胸病人,按照抛硬币法分组为观察组(自体血胸腔注射)22例和对照组(香菇多糖胸腔注射)24例;两组病人先行1000 mL生理盐水冲洗胸腔,使肺表面纤维条索粘连带冲洗干净;观察组以自体血80 mL,自胸管注入胸腔;对照组以香菇多糖4 mg+0.9%氯化钠注射液50 mL,自胸管注入胸腔。比较两组治疗效果、手术后住院时间及不良反应。结果观察组有效率为95.5%(21/22),对照组有效率为66.7%(16/24),两组之间差异有统计学意义。观察组和对照组手术后住院时间分别为(4.95±0.84)d和(7.96±1.85)d,差异有统计学意义。观察组不良反应也明显少于对照组,差异有统计学意义。结论自体血胸腔注射促进肺部手术术后气胸胸膜粘连治疗,效果明显,具有住院时间短和不良反应少,值得临床推广应用。Objective To compare the clinical efficacy and side effects of pleural adhesion promoted by autologous blood injection and lentinan injection on postoperative pulmonary air leakage.Methods From January 2019 to August 2022,a total of 46 patients with air leakage after lung surgery in The Third People's Hospital of Hefei(Hefei Third Clinical College of Anhui Medical University)were coin toss divided into the observation group(autologous blood thoracic injection)of 22 patients and the control group(lentinan thoracic injection)of 24 patients.In the two groups,the chest cavity was first flushed with 1000 mL normal saline to clean the fibrous bands on the lung surface;In the observation group,80 mL autologous blood was injected into the thoracic cavity through a thoracic catheter;In the control group,lentinan 4 mg+0.9%sodium chloride injection 50 mL was injected into the thoracic cavity through a chest catheter.The treatment effect,average hospitalization time and adverse reactions of the two groups were compared.Results The effective rate of the observation group was 95.5%(21/22),and that of the control group was 66.7%(16/24).The difference between the two groups was statistically significant.The average hospital stay after operation in the observation group and the control group was(4.95±0.84)days and(7.96±1.85)days,with a statistically significant difference.The adverse reactions in the observation group were also significantly less than those in the control group,with a statistically significant difference.Conclusion Intrathoracic injection of autologous blood can promote the treatment of pleural adhesions with air leakage after pulmonary surgery,with obvious effect,short hospitalization time and less adverse reactions,which is worthy of clinical application..

关 键 词：肺切除术 气胸 自体血 香菇多糖 胸腔注射 

分 类 号：R655.3[医药卫生—外科学]